Standards & Guidelines
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The 2023 ISHLT Guidelines for Mechanical Circulatory Support: A 10-Year Update25 May 2023
In 2013, ISHLT published the first official guidelines for implantable MCS. Ten years later, the update is available.
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The ISHLT/HFSA Guideline on Acute Mechanical Circulatory Support6 February 2023
A collaborative effort commissioned by ISHLT and HFSA has developed this critically-needed guideline for the management of patients requiring acute mechanical circulatory support.
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ISHLT Guidelines for the Care of Heart Transplant RecipientsEndorsed by the Pediatric Heart Transplant Society20 December 2022
The ISHLT Guidelines for the Care of HTX Recipients updates the 2010 Guidelines to reflect advances made in the last 10+ years and to identify remaining gaps, with the goal of guiding transplant programs and encouraging further research to close gaps.
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Reproductive Health after Thoracic TransplantationAn ISHLT Expert Consensus Statement25 October 2022
The goal of this statement is to summarize the current evidence and provide guidance surrounding preconception counseling, patient risk assessment, medical management, maternal and fetal outcomes, obstetric management, and pharmacologic considerations.
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Donor Heart Selection: Evidence-Based Guidelines for Providers20 September 2022
These guidelines provide evidence-based and expert-consensus recommendations for the selection of donor hearts following brain death. These recommendations were compiled by an international panel of experts based on an extensive literature review.
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Consensus Recommendations for Use of Maintenance Immunosuppression in Solid Organ Transplantation29 August 2022
These consensus recommendations are intended to provide transplant clinicians with a summary of literature on maintenance immunosuppression in the modern era and to support transplant team members working to secure medication access for patients.
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2022 ESC/ERS Guidelines for the Diagnosis and Treatment of Pulmonary Hypertension26 August 2022
These comprehensive clinical practice guidelines from ESC and ERS cover the whole spectrum of PH, with an emphasis on diagnosing and treating pulmonary arterial hypertension (PAH) and chronic thrombo-embolic pulmonary hypertension (CTEPH).
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ISHLT Statement on Transplant Ethics27 June 2022
ISHLT holds that there should be explicit policies, open to public scrutiny, governing all aspects of organ/tissue donation and transplantation, including the management of waiting lists for organs to ensure fair and appropriate access to transplantation.
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Peri-operative Management of Patients with Pulmonary Hypertension and Right Heart Failure Undergoing Surgery23 June 2022
This document represents the first international consensus statement for the perioperative management of patients with pulmonary hypertension and right heart failure.
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SCAI SHOCK Stage Classification Expert Consensus UpdateA Review and Incorporation of Validation Studies31 January 2022
In January 2022, ISHLT endorsed this updated document from the Society for Cardiovascular Angiography and Interventions (SCAI) regarding shock stage classification.
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Evaluation and Management of Patients with Chronic Thromboembolic Pulmonary Hypertension - Consensus Statement from ISHLT2 August 2021
This document is a literature review of chronic thromboembolic pulmonary hypertension. Due to the limited number of comparative trials in this field, the document includes expert opinion rather than recommendations based on levels of evidence.
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ISHLT Consensus Document on Lung Transplantation in Patients with Connective Tissue Disease: Part IEpidemiology, Assessment of Extrapulmonary Conditions, Candidate Evaluation, Selection Criteria, and Pathology Statements28 July 2021
This document clarifies disease definitions, describes the extrapulmonary manifestations requiring consideration before LTX, and outlines contraindications to transplantation allowing risk stratification during evaluation and selection of LTX candidates.
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International Consensus Recommendations for Anesthetic and Intensive Care Management of Lung TransplantationAn EACTAIC, SCA, ISHLT, ESOT, ESTS, and AST Approved Document26 July 2021
This joint endeavor by EACTAIC, SCA, ISHLT, ESOT, ESTS, and AST identifies potentially modifiable perioperative risks that provide novel opportunities for improved anesthesia and intensive care management strategies.
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Consensus Document for the Selection of Lung Transplant Candidates: An Update from ISHLT24 July 2021
This document assists providers caring for patients with pulmonary disease identify potential candidates for LTX, optimize referral timing of these patients to LTX centers, and provide LTX centers with a framework for evaluating and selecting candidates.
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ISHLT Consensus Statement for the Selection and Management of Pediatric and Congenital Heart Disease Patients on Ventricular Assist DevicesEndorsed by the American Heart Association19 May 2021
This consensus document was developed to address the selection and management of pediatric and congenital heart disease (CHD) patients undergoing VAD implantation.
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2021 ACC/AHA Key Data Elements and Definitions for Heart FailureA Report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards23 March 2021
Heart failure (HF) data standards are of critical importance, now more than ever. These data elements are intended to be useful across various categories related to the treatment of HF.
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2020 ACC/AHA Clinical Performance and Quality Measures for Adults With Heart FailureA Report of the ACC/AHA Task Force on Performance Measures2 November 2020
Developed as an update to the existing 2011 performance measures set, this document describes performance measures for heart failure and developing new measures to evaluation patient care based on the 2017 ACC/AHA/HFSA heart failure guideline update.
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ISHLT Consensus Statement for the Standardization of Bronchoalveolar Lavage in Lung Transplantation14 July 2020
This ISHLT Consensus Document on Bronchoalveolar lavage (BAL) standardization aims to enhance standardization and multi-center collaboration within the international LTX community and enable improvement and development of new BAL-based diagnostics.
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Report from the 2018 Consensus Conference on Immunomodulating Agents in Thoracic TransplantationAccess, Formulations, Generics, Therapeutic Drug Monitoring, and Special Populations9 July 2020
The aim of this consensus document is to address concerns generic drug immunosuppression, expand on the challenges and barriers, and provide therapeutic considerations for practitioners who manage cardiothoracic transplant patients.
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Donor Heart and Lung Procurement: A Consensus Statement21 April 2020
This international consensus statement is designed to serve as a guide for physicians, surgeons, and other providers who manage donors to best optimize the clinical status for the procurement of both heart and lungs for transplantation.

