Reproductive Health after Thoracic Transplantation
An ISHLT Expert Consensus Statement
Published 25 October 2022
Michelle M. Kittleson, MD, PhD; Ersilia M. DeFilippis, MD; Catriona J. Bhagra, MRCP, MD; Jillian P. Casale, PharmD; Matthew Cauldwell, MD; Lisa A. Coscia, RN, BSN, CCTC; Rohan D'Souza, MD; Nicole Gaffney, MD; Vicky Gerovasili, MD; Patricia Ging, MSc; Kristin Horsley, PhD; Francesca Macera, MD; Joan M. Mastrobattista, MD; Miranda A. Paraskeva, MD; Lynn R. Punnoose, MD; Kismet D. Rasmusson, DNP, FNP; Quitterie Reynaud, MD, PhD; Heather J. Ross, MD; Mitesh V. Thakrar, MD; Mary Norine Walsh, MD
J Heart Lung Transplantation Mar 2023;42(3):E1-E42.
Pregnancy after thoracic organ transplantation is feasible for select individuals but requires multidisciplinary subspecialty care. Key components for a successful pregnancy after lung or heart transplantation include preconception and contraceptive planning, thorough risk stratification, optimization of maternal comorbidities and fetal health through careful monitoring, and open communication with shared decision-making.
The goal of this consensus statement is to summarize the current evidence and provide guidance surrounding preconception counseling, patient risk assessment, medical management, maternal and fetal outcomes, obstetric management, and pharmacologic considerations.
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