The ASSIST-CLAD Study on JHLT the Podcast: Do Mesenchymal Stromal Cells help New-Onset CLAD?

Published 19 August 2026
  • Advanced Lung Failure & Transplantation
  • JHLT
  • News
  • Pharmacy
  • Podcast
  • Pulmonology

The ASSIST CLAD study on JHLT the Podcast with guest Daniel ChambersJHLT: the Podcast returns to the lung side of cardiothoracic transplantation with the study, "The ASSIST CLAD study: A phase 2 randomized controlled trial of mesenchymal stromal cells for new-onset chronic lung allograft dysfunction," which appears in the August print issue of JHLT.

Today's guest is Daniel C. Chambers, MBBS, MD, of The Prince Charles Hospital and Queensland Lung Transplant Service in Brisbane, Australia.

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In this episode, Dr. Chambers and Digital Editor Erika Lease discuss:

  • What inspired the team to explore the use of mesenchymal stromal cell (MSC) infusions in CLAD patients
  • Preparation and treatment considerations for using MSCs
  • How despite the negative outcome—the MSCs made no clear improvements in the patient groups—the study still pushes the field forward

For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.

Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation for a free subscription, or subscribe today at www.jhltonline.org.

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Stream the podcast on Spotify, Amazon, iTunes, and anywhere else you get podcasts.