JHLT The Podcast: Metabolic and transcriptomic insights on donor hearts with temperature controlled hypothermic preservation

Published 06 August 2025
  • Advanced Heart Failure & Transplantation
  • Cardiology
  • JHLT
  • News
  • Podcast

JHLT the podcast logo with Gaurav Sharma's headshot and the title of the publication

On the first August episode of JHLT: The Podcast, the Digital Media Editors invite first author Gaurav Sharma, PhD, MBA, from the University of Texas Southwestern Medical Center in Dallas. Dr. Sharma discusses his paper, " Metabolic and transcriptomic insights into temperature controlled hypothermic preservation of human donor hearts."

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You can also stream the podcast on Spotify, Amazon, iTunes, and anywhere else you get podcasts.

 

In the episode, you'll hear about:

  • How donor hearts not offered or declined for transplantation responded in hypothermic preservation versus conventional static cold storage
  • Potentially beneficial genetic signatures yielded by TCHP versus cold storage
  • The surprising response of energy stores in the hearts to the different storage environments
  • How multi-omic approaches could be applied to other organs

For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at  www.ishlt.org/jhlt.

Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.