NEW: ISHLT Early Career & Trainee Research Grant on Molecular and/or Genetic Biomarkers for Advanced Organ Failure & Post-Transplant Care

1. For early career applicants: The applicant must have completed their most recent training fewer than six years ago AND have obtained their first appointment less than six years ago at the time of the application.
2. For mentored trainees: The applicant must be actively in training during the grant period, performing research under the motorship of a principal investigator. Examples of trainees include undergraduate students, graduate students (Masters, PhD), medical students, residents, fellows, post-doctoral fellows.
3. If there are unusual circumstances, please contact the grants committee ahead of time and explain these circumstances in the application.

1. The applicant must either have an academic appointment or clinical appointment or may be in training at an accredited institution.
2. A letter of institutional commitment from a division or department chair at the institution at which the research will be conducted must be provided.
3. If a mentored trainee, need to include a support letter from your mentor. Your mentor MUST to be a member of ISHLT.

1. The applicant must be an active member of ISHLT or have submitted a completed membership application by 30 September.
2. If a mentored trainee, both the trainee and mentor need to be an active member of ISHLT.

1. There are no restrictions on past or current funding.
   • The applicant may be a past or current recipient of ISHLT funding including Fellowship or Faculty Development research grants.
   • The applicant may currently hold career development awards, mentoring awards, or other independent research awards.
2. If the applicant is currently receiving funding for a project similar to the topics described in this request for applications, the applicant should explain how the funds of the grant would not overlap with the funds of the other research support.

1. Applicants who have a substantial relationship with Natera that would present a real or perceived conflict of interest if awarded this grant must first contact ISHLT to declare the conflict before submitting an application. Examples of a substantial relationship with an industry partner include board member, member of advisory council, consultant, lecturer, etc.
2. Employees of Natera cannot submit an application.
3. Upon disclosure, the Grants Committee will determine if the individual is eligible to submit an application and will notify the individual in a timely manner.

Please review these guidelines and terms prior to completing your application. If you are ultimately awarded a grant, you will sign a letter of agreement (LOA) stating that you agree to these funding guidelines and terms, and the LOA will be co-signed by your institution’s grants/research office.

1. Research is anticipated to begin between January and June of the following year.
2. Funding in the amount of $40,000 will be provided for the research project.
3. Funding will not be released until visa status is confirmed (if applicable).
4. The grant is intended to provide salary support for the researcher, other study personnel, statistical support, supplies/materials, animals, core facilities, publication costs and travel related costs for abstract presentation. Up to 10 percent of the grant can be used for institutional overhead. No other costs are permitted.
5. The grant will be paid in multiple installments to the recipient’s institution. First installment (50% of funds) will be paid at the beginning of grant work; the second installment (25%) will be paid mid-award (after receipt of a grant progress report) and the final installment (25%) will be paid after receipt of a final report.
6. Grant funding is generally not transferable from one recipient to another; transfer may be considered under compelling circumstances (e.g., the grantee leaves the institution and does not request a transfer of the grant, or the grantee requires an extended medical leave).
7. If the grantee relocates and requests to move the grant to the new institution, the Grants Committee will determine whether the grant can be transferred to the recipient’s new location, or if the grant must be surrendered and any remaining funds returned. If the grant is surrendered, a final report will still be required.
8. If the grantee relocates and does not request a transfer of the grant to the new institution, the current institution (i.e., department chair or division chair and Office of Sponsored Research) may select a new PI. The Grants Committee will determine if the grant can be continued at the current institution.
9. The applicant must acknowledge the grant as a funding source in all manuscripts and presentations derived from the funded research using the following statement: “This work was supported by a grant from Natera and the International Society for Heart and Lung Transplantation.” Copies of such publications must be submitted to ISHLT.
10. Pursuant to regulations of the federal Physician Payment Sunshine Act (included in the Affordable Care Act), NPI numbers will be collected from grant recipients (if applicable), and tax ID numbers collected from the recipients’ institutions (if applicable). All payments will be reported to the Centers for Medicare and Medicaid Services Open Payments system, as payments from ISHLT represent indirect transfers of value from the funding pharmaceutical company.
11. Reports are required at the following intervals depending on the term of the grant, and continuation of funding is contingent upon completion of these reports:
    1. Mid-award progress report due six months after research start date.
    2. Final report within 30 days of the conclusion of the grant term.
       1. A final report is required even if the grant is surrendered for any reason prior to the conclusion of the grant term.

1. Selection of the grant recipient will be made by an expert review committee. The Grants Committee will identify experts who will review the applications from among those who applied during the open call for Grant Reviewers. In case of a very close or tie scores, the ISHLT Grants Committee will make the final decision. Consultation from expert reviewer(s) may be requested.
2. Grants will be scored on the basis of study aims, significance, innovation, research approach, feasibility of obtaining relevant data, and prior work, as well as other factors.
3. All applicants will be notified as to whether or not they have been selected to receive the research grant by 20 November.
4. For the individual selected, the term of the grant will be one year beginning between January – December of the  of year following grant submission.