New ISHLT Document on Acute Lung Allograft Dysfunction (ALAD)

Published 13 May 2026
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A new ISHLT Document, ISHLT Consensus Statement on Acute Lung Allograft Dysfunction (ALAD): Definition, Etiology, Diagnostic and Therapeutic Approaches, and Research Priorities, has been published in JHLT and is available to read online!

Led by Stephen Juvet, Ciara Shaver, and Greg Snell, this document was developed to address several needs identified during the ALAD Symposium held during the ISHLT Annual Meeting in April 2024. ISHLT assembled a multinational, multidisciplinary diverse group of ISHLT members to generate a consensus statement on ALAD. The group included transplant pulmonologists, transplant surgeons, infectious disease specialists, pathologists, pediatricians, pharmacists, and scientists from 16 different countries on 4 continents.

The primary aims of this ISHLT Consensus Statement on ALAD are to standardize the nomenclature of ALAD, define its contributing etiologies, provide a suggested framework for diagnostic testing and therapeutic decision making, and identify research opportunities to facilitate collaboration and benchmarking among transplant centers in investigating the pathogenesis, possible prevention, and further treatment of ALAD.

Visit the Standards & Guidelines page for details, top takeaways, and links to read or download the document.