New ISHLT Document on Graft Dysfunction after Heart Transplantation

Published 13 March 2026
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A new ISHLT Document, Summary of the ISHLT Consensus Conference on Graft Dysfunction within the First 72 hours after Heart Transplantation: A 10-year Update, has been published in JHLT and is available to read online!

Led by Jon Kobashigawa, this document is a summary of the consensus conference held in Prague, Czech Republic in 2024 as part of a 10-year update to the 2013-2014 ISHLT Consensus Conference on PGD. The conference represented a collaborative multidisciplinary effort by experts in cardiac transplantation worldwide to update current definitions and classifications of graft dysfunction, enrich the heart transplant community understanding of its risk factors and biomarkers, delve into potential prevention and management strategies, and unwind primary graft dysfunction overlap with vasoplegia.

Over the past decade, there has been a growing understanding of primary graft dysfunction, current practices remain variable, attributable to a lack of objective data and largely influenced by center-specific practices. This document aims to provide a more standardized pathway for the prevention, diagnosis, and management of graft dysfunction after heart transplantation and pave the way for future studies.

Visit the Standards & Guidelines page for details, top takeaways, and links to read or download the document.