Late-Breaking Clinical Science Abstracts


The late-breaking clinical science category is intended to facilitate the presentation of high-impact multi-center studies or particularly provocative single-center investigations. In general, such studies would include prospective, randomized trials that seek to investigate new approaches to the diagnosis and/or treatment of cardiothoracic diseases relevant to the field and that have the potential to alter our contemporary treatment paradigm.

To assure that truly "late-breaking" information is included in the meeting, authors may submit abstracts describing trials and studies that are not yet completed as of October 27, 2020 but WILL have results and conclusions available by April 12, 2021. The abstract must be submitted by the October 27 deadline and will serve as a placeholder for the final abstract.
  • A study which has results and conclusions by October 27, 2020 is not considered late-breaking and should be submitted as a research abstract.
  • Abstracts presenting an interim analysis of clinical trial data will not be accepted unless the intention to conduct an interim analysis was predetermined in the trial protocol before the study commenced.
  • All late-breaking clinical science abstracts accepted for presentation must undergo a final review of the study results and conclusions by the Executive Program Committee in early April 2021. ISHLT reserves the final decision regarding scheduling of Late-Breaking Clinical Science presentations.


A late-breaking clinical science abstract submission must include the following information (limited to 2,140 characters, not including spaces):
  • Title
  • Statement of Purpose of the study (goal or hypothesis being tested)
  • Methods and Procedures used
  • Endpoints
Note: abstracts undergo a blind review process; therefore, abstain from using institution and corporate names within the abstract. If accepted, you may update your abstract accordingly.


The Full Name, Affiliation, Email Address, and Disclosure Statement for the Presenting Author and each co-author must be included. There is no limit to the number of authors, and author information is not counted towards the character limit.

The Presenting Author will be the only author to receive notification of acceptance/rejection of a submitted abstract; therefore, it is the Presenting Author's responsibility to notify all co-authors regarding the outcome of an abstract submission.

Submission Categories

A late-breaking clinical science abstract may be submitted into one of four categories:
  • Advanced Heart Failure and Transplantation (HEART)
  • Advanced Lung Failure and Transplantation (LUNG)
  • Mechanical Circulatory Support (MCS)
  • Pulmonary Vascular Disease (PVD)


Accepted Late-Breaking Clinical Science abstracts will be published exactly as submitted in the April 2021 Supplement of the Journal of Heart and Lung Transplantation. If you would like an updated version of your abstract with interim results published, you must submit these results to no later than February 5, 2021.

Visit our FAQ Page for answers to common submission questions.