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Primary Audience: BSTR
Secondary Audience: LF/LTX, PATH

Session Summary: The pathologies of Chronic Lung Allograft Dysfunction (CLAD) have been recognized since 1984, yet their mechanisms and definitive treatments remain enigmatic. Indeed, there are multiple rival hypotheses as to the cause of CLAD. Is CLAD a final common pathway, an integration of pathobiologies, or are some pathways overriding? This symposium will describe the scientific evidence for some of these pathways.

Chairs: Sangeeta M. Bhorade, MD and Stijn E. Verleden, MD, PhD
 

7:00 AM	Immune Responses Cause CLAD Federica Meloni, MD, University of Pavia, Pavia, Italy
7:15 AM	CLAD is a Disease of Accelerated Aging John R. Greenland, MD, PhD, UCSF Medical Center, San Francisco, CA, USA
7:30 AM	Mesenchymal Stem Cells are the Cause of CLAD Vibha N. Lama, MD, MS, University of Michigan, Ann Arbor, MI, USA
7:45 AM	15-min Panel Discussion

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Primary Audience: HF/HTX
Secondary Audience: MCS

Session Summary: This symposium will provide an overview of the potential alternatives to and fresh ideas for organ transplantation. Each speaker will provide an overview of the “state of the art” in their respective area of organ repair, regeneration or replacement, and will give insight into successes, challenges and potential of their respective areas, incorporating discussion of the clinical feasibility, ethics and potential of the respective therapies.

Chairs: Mrinalini Krishnan, MD and Ulrich Steinseifer, MD
 

7:00 AM	Copy and Paste vs. Renovate: Cardiac 3D Printing and Its Future Direction Doris A. Taylor, PhD, FAHA, FACC, Texas Heart Institute, Houston, TX, USA
7:15 AM	‘When Pigs Fly’: Where Are We Now with Xenotransplantation? Richard Pierson, MD, Massachusetts General Hospital, Boston, MA, USA
7:30 AM	Hitting Reset: Utility of Stem Cells to Regenerate the Heart Sonja Schrepfer, MD, PhD, UCSF Medical Center, San Francisco, CA, USA
7:45 AM	15-min Panel Discussion

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Primary Audience: ID
Secondary Audience: MCS

Session Summary: Infections are a leading cause of death in VAD recipients, and are associated with morbidity, readmissions and healthcare costs. This symposium will focus on state of the art updates on the prevalence of VAD infections and their consequences including neurologic complications. Infection control and quality practices can impact the rate of infections. The recent ISHLT consensus document discussing the prevention and management of MCS infections will be reviewed.

Chairs: Saima Aslam, MD, MS and Jan D. Schmitto, MD, PhD, MBA
 

7:00 AM	What are the Consequences of a VAD Infection? Palak Shah, MD, MS, Inova Fairfax Hospital, Falls Church, VA, USA
7:15 AM	Q&A
7:20 AM	Infection Prevention for Patients with Mechanical Circulatory Support Margaret Hannan, MD, Mater Hospital, Dublin, Ireland
7:35 AM	Q&A
7:40 AM	Molecular Pathogenesis and Diagnostic Strategies for MCS Infections Anton Peleg, MD, PhD, MPH, The Alfred Hospital and Monash University, Melbourne, Australia
7:55 AM	Q&A

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Primary Audience: MCS
Secondary Audience: BSTR, PATH

Session Summary: Mechanical unloading of the left ventricle is a potent platform through which to study reverse remodeling. While we now understand that sufficient “recovery” to allow for device explantation is realistic in only a select population, the concept of reverse remodeling during LVAD still has much broader application. This symposium will highlight reverse remodeling during MCS starting with basic physiology and moving through clinical topics and commencing with a view to the future.

Chairs: Ivan Netuka, MD, PhD and Joyce W. Wald, DO
 

7:00 AM	Cardiac Recovery on Acute Mechanical Support - When to Wean and When to Transition Anna L. Meyer, MD, Leipzig Heart Center, Leipzig, Germany
7:15 AM	Q&A
7:20 AM	LVAD Explantation for Cardiac Recovery – Who, When, and How Snehal R. Patel, MD, Montefiore Medical Center, Bronx, NY, USA
7:35 AM	Q&A
7:40 AM	Present and Future of Cardiac Recovery and Durable MCS Stavros G. Drakos, MD, PhD, FACC, University of Utah School of Medicine, Salt Lake City, UT, USA
7:55 AM	Q&A

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Primary Audience: NHSAH

Session Summary: Research has led to incredible advancements in organ failure/transplant outcomes. Despite its significance, not all transplant professionals have training or experience in the conduct of research. Launching (or continuing) a program of research can be intimidating for many. Experts in the field will provide guidance on the conduct of research from study development to dissemination findings. Tips for funding one's research will also be shared.

Chairs: Mary Amanda Dew, PhD and Sarah Schettle, PA-C
 

7:00 AM	Don’t Go Rogue: Planning and Launching a Research Study Pamela Combs, PhD, RN, University of Chicago, Chicago, IL, USA
7:15 AM	The Fallout: Dissemination and Sharing your Results Desiree Robson, RN BSc (Hons), St. Vincent’s Hospital, Sydney, Australia
7:30 AM	The Ghost Hunt: Funding Your Research Kathleen L. Grady, PhD, APN, FAAN, Northwestern Memorial Hospital, Chicago, IL, USA
7:45 AM	15-min Panel Discussion

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Primary Audience: PHARM
Secondary Audience: MCS

Session Summary: This symposium will aim to review pharmacotherapy management of hematologic complications in transplant and MCS including neutropenia, thrombocytopenia, anticoagulation with direct oral anticoagulants (DOACs), hemoglobin optimization, and bleeding reversal.

Chairs: Bastian Schmack, MD and Kyle L. Dawson, PharmD, MBA, BCPS
 

7:00 AM	I've Got Friends with Low Platelets (and Neutrophils): Management of Cytopenias After Transplant Jennifer McDermott, PharmD, Spectrum Health, Grand Rapids, MI, USA
7:15 AM	Q&A
7:20 AM	Thicker than Blood: Using DOACs in Transplantation and MCS Sara Strout, PharmD, Johns Hopkins, MD, USA
7:35 AM	Q&A
7:40 AM	Ain't No Hemoglobin High Enough: Approaches to Hemoglobin Optimization and Bleeding Reversal Pre- and Post-Surgery Ian B. Hollis, PharmD, BCPS, University of North Carolina Medical Center, Chapel Hill, NC, USA
7:55 AM	Q&A

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Primary Audience: ALL

Chairs: David O. Taylor, MD and Lori J. West, MD, DPhil
 

8:00 AM	New Perspectives on Tolerance Sing Sing Way, MD, PhD, Cincinnati Children’s Hospital, Cincinnati, OH, USA
8:20 AM	(3) Safety and Efficacy of Bacteriophage Therapy in Lung Transplant Candidates and Recipients A. Courtwright1, C. Koval2, S. Lehman3, S. Morales3, C. L. Furr3, F. Rosas3, M. Brownstein4, J. Fackler4, B. M. Sisson4, B. Biswas5, R. T. Schooley6, S. Aslam6. 1Pulmonary and Critical Care Medicine, University of Pennsylvania, Philadelphia, PA, 2Department of Infectious Diseases, Cleveland Clinic Foundation, Cleveland, OH, 3AmpliPhi Biosciences, San Diego, CA, 4Adaptive Phage Therapeutics, Gaithersburg, MD, 5Naval Medical Research Center, Fort Detrick, MD, 6Department of Infectious Diseases, UC San Diego, San Diego, CA
8:35 AM	Expert Interactive Discussant for Safety and Efficacy of Bacteriophage Therapy in Lung Transplant Candidates and Recipients Fernanda Silveira, MD, University of Pittsburgh, Pittsburgh, PA, USA
8:40 AM	(4) Increased Volume, Improved Quality, and Better Outcomes Using a Specialized Thoracic Adapted Recovery (STAR) Model for Thoracic Transplantation: Experience from 1000 Cases H. Tetteh1, P. Brandenhoff2, R. S. Higgins3. 1Department of Surgery, Uniformed Services University, Bethesda, MD, 2Cardiothoracic Surgery, Thoracic Transplant Consultants, San Francisco, CA, 3Department of Surgery, Johns Hopkins University, Baltimore, MD
8:55 AM	Expert Interactive Discussant for Increased Volume, Improved Quality, and Better Outcomes Using a Specialized Thoracic Adapted Recovery (STAR) Model for Thoracic Transplantation: Experience from 1000 Cases Andreas Zuckermann, MD, Medical University of Vienna, Vienna, Austria
9:00 AM	Transplant from Every Angle Susan Hou, MD, Loyola University Medical Center, Maywood, IL, USA
9:20 AM	Countdown to Teamwork Colonel Mike Mullane, Astronaut, Albuquerque, NM, USA

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Primary Audience: HF/HTX
Secondary Audience: BSTR, PATH

Chairs: Yoshikatsu Saiki, MD, PhD and Evan P. Kransdorf, MD, PhD
 

10:30 AM	(217) Identification of Latent Classes of Cardiac Allograft Vasculopathy Trajectories after Heart Transplantation and Their Determinants G. Coutance1, M. Racapé2, G. Bonnet3, M. Raynaud2, J. Van Keer2, M. Bories3, P. Bruneval3, J. Duong Van Huyen4, J. Taupin5, S. Varnous6, R. Guillemain7, X. Jouven3, A. Loupy4. 1Paris Transplant Group, Pitié-Salpêtrière Hospital, Paris, France, 2Paris Transplant Group, Paris, France, 3Paris Transplant Group, Hôpital Européen Georges Pompidou, Paris, France, 4Paris Transplant Group, Necker Hospital, Paris, France, 5Saint Louis Hospital, Paris, France, 6Pitié-Salpêtrière Hospital, Paris, France, 7Hôpital Européen Georges Pompidou, Paris, France
10:45 AM	(218) Leukotriene B4 Contributes to Development of Cardiac Allograft Vasculopathy K. K. Khush1, D. Wang2, G. Tediashvili2, H. Luikart1, N. D'Emilio1, Y. Moayedi1, S. Schrepfer2. 1Stanford University, Stanford, CA, 2University of California San Francisco, San Francisco, CA
11:00 AM	(219) Novel Descriptors of Coronary Wall Properties Measured by OCT at Baseline Are Associated with CAV-Related Intimal Thickening One Year after Heart Transplant Z. Chen1, M. Pazdernik2, A. Wahle1, H. Zhang1, V. Melenovsky2, J. Kautzner2, V. Karmazin2, H. Bedanova3, A. Tomasek3, E. Ozabalova3, M. Sonka1. 1University of Iowa, Iowa City, IA, 2Institute of Clinical and Experimental Medicine (IKEM), Prague, Czech Republic, 3Cardiovascular and Transplantation Surgery Center, St. Annes University Hospital and Masaryk University Brno, Brno, Czech Republic
11:15 AM	(220) Low Serum Magnesium is Associated with Increased Mortality and Cardiac Allograft Vasculopathy Following Heart Transplantation Y. Peled1, J. Lavee1, N. Shlomo2, T. Cohen2, A. Kogan1, E. Maor1, M. Shechter1, D. Freimark1, R. Klempfner1. 1Sheba Medical Center Tel Hashomer and Tel-Aviv University, Ramat Gan, Israel, 2Israeli Association for Cardiovascular Trials, Ramat Gan, Israel
11:30 AM	(221) Increased Platelet Aggregation in Heart Transplant Recipients with Cardiac Allograft Vasculopathy K. P. Bjerre1, K. Berg1, T. S. Clemmensen2, S. H. Poulsen1, S. D. Kristensen1, A. Hvas1, E. L. Grove1, H. Eiskjær1. 1Aarhus University Hospital, Aarhus N, Denmark, 2Horsens Regional Hospital, Horsens, Denmark
11:45 AM	(222) Mild Acute Cellular Rejection is Not Associated with Development of Cardiac Allograft Vasculopathy Assessed by Intravascular Ultrasound and Coronary Angiography in Heart Transplant Recipients - A Substudy of the SCHEDULE Trial L. M. Nelson1, A. K. Andreassen2, S. Arora2, B. Andersson3, E. Gude2, H. Eiskjær4, G. Rådegran5, G. Dellgren6, L. Gullestad7, F. Gustafsson1. 1Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark, 2Department of Cardiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway, 3Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden, 4Department of Cardiology, Aarhus University Hospital, Skejby, Aarhus, Denmark, 5The Clinic for Heart Failure and Valvular Disease, Skåne University Hospital and Lund University, Lund, Sweden, 6Transplant Institute, Sahlgrenska University Hospital, Gothenburg, Sweden, 7Department of Cardiology, Oslo University Hospital, Rikshospitalet, and University of Oslo, Oslo, Norway
12:00 PM	(223) Are Gene Expression Profile Testing Scores Associated with New Onset Cardiac Allograft Vasculopathy? A. Lala1, D. Hiller2, J. Yee2, K. Khush3, R. Alharethi4, S. Pinney5. 1Medicine, Cardiology, Population Health Science, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY, 2CareDx, Brisbane, CA, 3Stanford University School of Medicine, Stanford, CA, 4University of Utah School of Medicine, Salt Lake City, UT, 5Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY

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Primary Audience: HF/HTX

Session Summary: In collaboration with the Society for Cardiovascular Magnetic Resonance (SCMR), this symposium will address how CMR advances in structural and functional imaging techniques have led to better cardiac tissue and anatomical characterization in complex patients. We will address its clinical role in the management of cardiomyopathies and heart transplant and explore pathological and imaging relationships while addressing standard and novel CMR based diagnostic approaches including contrast free imaging and imaging in patients with pacemakers.

Chairs: Daniel Kim, MD and Sonya Babu-Narayan, MBBS, BSc, PhD
 

10:30 AM	MRI Sequences and Pathologic Correlates: The First Face of Janus Annalisa Angelini, MD, University of Padua, Padua, Italy
10:45 AM	MRI Sequences and Pathologic Correlates: The Second Face of Janus Timothy C. Wong, MD, MS, University of Pittsburg, Pittsburg, PA, USA
11:00 AM	Q&A
11:05 AM	CMR and Cardiomyopathies: A World Beyond Speckles Victor A. Ferrari, MD, Perelman School of Medicine, Philadelphia, PA, USA
11:20 AM	CASE PRESENTATION: A Post-Transplant Patient with New Worsening of LV Function Mandar Aras, MD, UCSF Medical Center, San Francisco, CA, USA
11:25 AM	CMR and Heart Transplantation: One Stop Shop? Sofia C. Masri, MD, University of Washington, Seattle, WA, USA
11:40 AM	CASE PRESENTATION: Patient with CHD and New Echocardiographic Findings: What Next? Chesney Castleberry, MD, Washington University in St. Louis, St. Louis, MO, USA
11:45 AM	CMR and Congenital Heart Disease: Not as Baffling as You Thought Sonya Babu-Narayan, MBBS, BSc, PhD, Imperial College London, London, UK
12:00 PM	15-min Panel Discussion

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Primary Audience: ID
Secondary Audience: MCS

Chairs: Margaret M. Hannan, MD and Christine E. Koval, MD
 

10:30 AM	(224) Increased Risk of Stroke and Death in Ventricular Assist Device Patients Varies by ISHLT Infection Category: An INTERMACS Analysis P. Shah1, S. E. Birk2, L. B. Cooper1, M. A. Psotka1, J. K. Kirklin3, S. D. Barnett1, S. B. Katugaha4, S. Phillips1, M. M. Looby5, F. D. Pagani6, J. A. Cowger7. 1Heart Failure and Transplantation, Inova Heart and Vascular Institute, Falls Church, VA, 2School of Public Health, George Washington University, Washington, DC, 3Cardiac Surgery, University of Alabama, Birmingham, AL, 4Transplant Infectious Diseases, Inova Heart and Vascular Institute, Falls Church, VA, 5Department of Pharmacy, Inova Heart and Vascular Institute, Falls Church, VA, 6Cardiac Surgery, University of Michigan, Ann Arbor, MI, 7Heart Failure and Transplantation, Henry Ford Hospital, Detroit, MI
10:45 AM	(225) Epidemiology, Outcomes, and Effects of Device Flow Type on Ventricular Assist Devices (VAD) Infections: An IMACS Registry Analysis R. Xie1, J. Cowger2, J. K. Kirklin1, M. M. Hannan3, D. J. Goldstein4, S. Aslam5. 1Department of Surgery, Division of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, AL, 2Henry Ford Hospitals, Farmington Hills, MI, 3Mater Misericordiae University Hospital, Dublin, Ireland, 4Department of Cardiovascular and Thoracic Surgery, Montefiore Medical Center, Bronx, NY, 5Division of Infectious Diseases and Global Public Health, University of California, San Diego, San Diego, CA
11:00 AM	(226) A Comprehensive In Vitro Evaluation of Medihoney as an Anti-Biofilm Agent in Preventing Ventricular Assist Device Driveline Infections Y. Qu1, D. McGiffin2, C. Kure2, J. McLean2, C. Duncan2, A. Y. Peleg1. 1Infectious Diseases, The Alfred Hospital and Monash University, Clayton, Australia, 2Cardiothoracic Surgery, The Alfred Hospital and Monash University, Melbourne, Australia
11:15 AM	(227) Efficacy of Pump Exchange with a Left Ventricular Assist Device Associated Infection L. Coyle, C. Gallagher, W. Cotts, P. Pappas, A. Tatooles. Heart and Vascular Institute, Advocate Christ Medical Center, Oak Lawn, IL
11:30 AM	(228) Primary versus Delayed Sternal Closure in Left Ventricular Assist Device Implantation Patients: Impact on Infection M. H. Akay1, M. Cakici1, M. Alagoz1, M. K. Patel1, M. K. Jezovnik1, M. Ilic1, I. Salas De Armas2, K. Rajagopal1, R. Radovancevic1, S. Kumar1, M. Jumean1, B. Kar1, I. D. Gregoric1. 1Department of Advanced Cardiopulmonary Therapies and Transplantation, The Univ. of Texas Health Science Center-Houston, Houston, TX, 2Department of Advanced Cardiopulmonary Therapies and Transplantation, The University of Texas Health Science Center-Houston, Houston, TX
11:45 AM	(229) Comparing the Incidence of Surgical Site Infections(SSI) Using Narrow versus Broad-Spectrum Perioperative Antibiotic Prophylaxis in Mechanical Circulatory Support (MCS) Patients L. D. Lam1, M. Payne-Cardona2, M. Fang2, R. Herra2, E. Coria Mondragon2, C. Runyan1, J. Moriguchi3, J. A. Kobashigawa3, L. S. Czer3, F. Arabia4, R. Zabner5. 1Mechanical Circulatory Support, Cedars Sinai Comprehensive Transplant Center, Los Angeles, CA, 2University of California, School of Pharmacy, San Francisco, CA, 3Cedars-Sinai Smidt Heart Institute, Los Angeles, CA, 4Advanced Heart Program, Banner/University of Arizona, Phoenix, AZ, 5Infectious Disease, Cedars Sinai Health System, Los Angeles, CA
12:00 PM	(230) A Study of Infected Drivelines from Ventricular Assist Device Patients: The Presence of Microbial Biofilms and Micro-Gaps in the Driveline Tunnel Y. Qu1, D. McGiffin2, C. Hayward3, D. Robson3, C. Kure2, H. Thissen4, S. Marasco2, A. Zimmet2, J. Negri2, P. Jansz5, K. Dhital5, A. Peleg1. 1Infectious Diseases, The Alfred Hospital and Monash University, Melbourne, Australia, 2Cardiothoracic Surgery, The Alfred Hospital and Monash University, Melbourne, Australia, 3Department of Cardiology, St Vincent’s Public Hospital, Sydney, Darlinghurst, Australia, 4CSIRO, Melbourne, Australia, 5Cardiothoracic Surgery, St Vincent’s Public Hospital, Sydney, Darlinghurst, Australia

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Primary Audience: LF/LTX
Secondary Audience: ID, PATH

Chairs: Stephane Collaud, MD and Walter Klepetko, MD
 

10:30 AM	(231) 5-Year Results from the ISHLT DCD Lung Transplant Registry Confirm Excellent Recipient Survival from Donation after Circulatory Death Donors D. E. Van Raemdonck1, S. Keshavjee2, B. Levvey3, W. S. Cherikh4, G. Snell3, M. E. Erasmus5, A. Simon6, A. Glanville7, S. Clark8, F. D'Ovidio9, P. Catarino10, K. McCurry11, M. Hertz12, R. Venkateswaran13, P. Hopkins14, I. Inci15, R. Walia16, D. Kreisel17, J. Mascaro18, D. F. Dilling19, P. Camp20, D. Mason21, M. Musk22, M. Burch23, A. Fisher8, R. Yusen17, J. Stehlik24, M. Cypel2. 1University Hospitals Leuven, Leuven, Belgium, 2University of Toronto, Toronto, ON, Canada, 3Alfred Hospital, Melbourne, Australia, 4UNOS, Richmond, VA, 5University Medical Center Groningen, Groningen, Netherlands, 6Harefield Hospital, London, United Kingdom, 7St Vincent's Hospital, Sydney, Australia, 8Freeman Hospital, Newcastle upon Tyne, United Kingdom, 9Columbia University Presbyterian Hospital, New York, NY, 10Royal Papworth Hospital, Cambridge, United Kingdom, 11Cleveland Clinic, Cleveland, OH, 12University of Minnesota, Minneapolis, MN, 13Wythenshawe Hospital, Manchester, United Kingdom, 14The Prince Charles Hospital, Brisbane, Australia, 15University Hospital Zurich, Zurich, Switzerland, 16St. Joseph's Hospital & Medical Center, Phoenix, AZ, 17Washington University, St Louis, MO, 18University Hospitals Birmingham, Birmingham, United Kingdom, 19Loyola University Medical Center, Chicago, IL, 20Brigham and Womens Hospital, Boston, MA, 21Baylor University Medical Center, Dallas, TX, 22Fiona Stanley Hospital, Perth, Australia, 23Great Ormond Street for Children, London, United Kingdom, 24University of Utah, Salt Lake City, UT
10:45 AM	(232) Estimated Impact of Hepatitis C Positive Lung Donor Utilization on US Donor Lung Supply J. Mooney, N. Purington, P. Mohabir, G. Dhillon. Department of Medicine, Stanford University School of Medicine, Stanford, CA
11:00 AM	(233) Center Variability in Organ Offer Acceptance and Waitlist Mortality in Lung Transplantation A. Y. Choi1, M. S. Mulvihill2, J. Weber3, H. Lee3, M. L. Cox2, B. A. Yerokun2, M. Kuchibhatla3, J. A. Klapper2, M. G. Hartwig2. 1Duke University School of Medicine, Durham, NC, 2Department of Surgery, Duke University Medical Center, Durham, NC, 3Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC
11:15 AM	(234) Donation after Circulatory Death (DCD): A 10-Year Experience in Bilateral Lung Allograft Survival at a Single Australian Center D. R. Darley, M. Benzimra, R. Pearson, M. Malouf, A. Glanville, A. Havryk, M. Plit. Lung Transplantation, St Vincent's Hospital, Sydney, Australia
11:30 AM	(235) The Impact of the Calculated Panel Reactive Antibody Value on Wait List Outcomes for Lung Transplant Candidates M. Aversa1, L. Benvenuto1, H. Kim1, L. Shah1, H. Robbins1, B. P. Stanifer1, F. D'Ovidio1, E. Vasilescu2, J. Sonett1, S. Arcasoy1. 1Lung Transplant Program, Columbia University Medical Center, New York, NY, 2Pathology and Cell Biology, Columbia University Medical Center, New York, NY
11:45 AM	(236) Utilization of PHS Increased Risk Donors in Lung Transplant Reduces Median Waitlist Time without Reducing Survival T. Khuu1, R. Chand2, C. Lum2, A. Salimbangon3, A. Chang1, D. Ross4, A. Ardehali5, E. DePasquale1. 1Transplant Services, UCLA, Los Angeles, CA, 2Medicine, Cardiology, UCLA, Los Angeles, CA, 3Transplant Service, UCLA, Los Angeles, CA, 4Medicine, Pulmonology, UCLA, Los Angeles, CA, 5Surgery, UCLA, Los Angeles, CA
12:00 PM	(237) Donor-Recipient Size Matching via Chest X-ray Measurements and Primary Graft Dysfunction Risk in Lung Transplantation D. Li, J. Weinkauf, D. Lien, A. Kapasi, A. Hirji, K. Halloran. Department of Medicine, University of Alberta, Edmonton, AB, Canada

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Primary Audience: MCS
Secondary Audience: NHSAH

Chairs: Stuart D. Russell, MD and Finn Gustafsson, MD, PhD
 

10:30 AM	(238) Sequential Chains of Adverse Events Post LVAD Implantation F. Movahedi1, R. L. Kormos2, L. Lohmueller3, L. Seese2, M. Kanwar4, S. Murali5, Y. Zhang6, R. Padman7, J. F. Antaki8. 1Electrical Engineering, University of Pittsburgh, Pittsburgh, PA, 2Medicine, Heart and Vascular Institute, Pittsburgh, PA, 3School of Computer Science, Carnegie Mellon University, Pittsburgh, PA, 4Electrical Engineering, Cardiovascular Institute at Allegheny General Hospital, Pittsburgh, PA, 5Cardiovascular Institute at Allegheny General Hospital, Pittsburgh, PA, 6Weill Cornell Medicine, Pittsburgh, NY, 7Heinz College of Information Systems and Public Policy, Pittsburgh, PA, 8Meinig School of Biomedical Engineering, Cornell University, Pittsburgh, PA
10:45 AM	(239) VE/VCO2 Predicts RV Dysfunction and Mortality after Left Ventricular Assist Device: A Fresh Look at Cardiopulmonary Stress Testing for Prognostication J. Grinstein1, Y. Sawalha2, M. Hofmeyer1, F. Sheikh1, M. Rodrigo1, A. Kadakkal1, C. Barnett1, S. Kalantari3, I. Talati4, R. Zaghlol2, E. Molina1, S. Mohammed1, S. Najjar1. 1MedStar Heart and Vascular Institute, Washington, DC, 2MedStar Washington Hospital Center, Washington, DC, 3University of Chicago, Chicago, IL, 4Georgetown University School of Medicine, Washington, DC
11:00 AM	(240) Features for Success: Factors Associated with Successful LVAD Outcomes at 1-Year Post Implant L. C. Lohmueller1, M. Kanwar2, S. Murali2, J. F. Antaki3. 1Language Technologies Institute, Carnegie Mellon University, Pittsburgh, PA, 2Cardiovascular Institute, Allegheny General Hospital, Pittsburgh, PA, 3Biomedical Engineering, Cornell University, Ithaca, NY
11:15 AM	(241) Derivation and Validation of the EUROMACS Left Ventricular Assist Device Score for Long-Term Outcome - The EUROMACS-LVAD-Score B. Schrage1, N. Rübsamen2, C. Magnussen1, J. Gummert3, F. Schönrath4, T. de By5, B. Meyns6, D. Westermann1, S. Blankenberg1, H. Reichenspurner1, A. Bernhardt1. 1University Heart Center Hamburg, Hamburg, Germany, 2University Heart Centre Hamburg, Hamburg, Germany, 3Heart and Diabetes Center Bad Oeynhausen, Bad Oeynhausen, Germany, 4German Heart Center Berlin, Berlin, Germany, 5EUROMACS, Windsor, United Kingdom, 6Cardiale Heelkunde, Leuven, Belgium
11:30 AM	(242) A Novel Model Incorporating Pectoralis Muscle Measures to Predict Mortality after Ventricular Assist Device Implantation R. Cogswell1, T. Murray2, R. Araujo3, L. Teigen1, B. Trachtenberg3, J. Schultz1, R. John4, C. Martin1, J. Estep5. 1Department of Medicine, Division of Cardiology, University of Minnesota, Minneapolis, MN, 2School of Public Health, Department of Biostatistics, University of Minnesota, Minneapolis, MN, 3Department of Medicine, Division of Cardiology, Houston Methodist, Houston, TX, 4Department of Surgery, Division of Cardiovascular Surgery, University of Minnesota, Minneapolis, MN, 5Department of Medicine, Division of Cardiology, Cleveland Clinic, Cleveland, OH
11:45 AM	(243) Heart Failure Severity Stratification beyond INTERMACS Profiles: A Step towards Identification of Optimal LVAD Implantation Timing R. Cogswell1, J. Estep2, R. Araujo3, L. Teigen1, J. Schultz1, R. John4, C. Martin1, B. Trachtenberg3. 1Department of Medicine, Division of Cardiology, University of Minnesota, Minneapolis, MN, 2Department of Medicine, Division of Cardiology, Cleveland Clinic, Cleveland, OH, 3Department of Medicine, Division of Cardiology, Houston Methodist, Houston, TX, 4Department of Surgery, Division of Cardiovascular Surgery, University of Minnesota, Minneapolis, MN
12:00 PM	(244) Geriatric Nutrition Risk Index is Associated with LVAD Recipient Survival with Cutoff Value of 92.68 M. Kawabori1, S. Lofftus2, A. Vest1, V. Pramil2, Y. Zhan1, K. G. Warner1, H. Rastegar1, M. S. Kiernan1, F. Y. Chen1, G. S. Couper1. 1Tufts Medical Center, Boston, MA, 2Tufts University School of Medicine, Boston, MA

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Primary Audience: PEDS
Secondary Audience: HTX, ID, LTX, NHSAH, PHARM

Session Summary: In collaboration with the International Pediatric Transplant Association (IPTA), this symposium will focus on EBV and CMV in pediatric thoracic transplantation. We will cover monitoring, prevention, current and emerging therapies for these entities in pediatric thoracic transplant candidates and recipients. The session will appeal to the following groups: pediatric heart and lung transplant physicians, advance practice nurses, nursing, transplant coordinators, infectious disease clinicians, pharmacists, and translational virologists.

Chairs: Brian Feingold, MD, MS and Klara Posfay-Barbe, MD, MS
 

10:30 AM	The A-B-C’s of EBV Monitoring in Pediatric Thoracic Transplant Recipients Upton Allen, MBBS, MSc, FAAP, FRCPC, University of Toronto/Sick Kids, Toronto, ON, Canada
10:45 AM	EBV Prevention in Pediatrics: Fantasy or Reality? Michael Green, MD, Children's Hospital of Pittsburgh, Pittsburgh, PA, USA
11:00 AM	First Line, Advanced, and Emerging Therapies for the Treatment of EBV Disease/PTLD in Pediatrics Steven A. Webber, MBChB, Vanderbilt University, Nashville, TN, USA
11:15 AM	Implications of EBV Disease on Long-Term Outcomes in Thoracic Transplant Recipients Matthew J. Bock, MD, Loma Linda University, Loma Linda, CA, USA
11:30 AM	PCRs, Cellular Immunity and Immunogenetic Biomarkers: We’ve Got You Now CMV! Klara Posfay-Barbe, MD, MS, Hopitaux Universitaires de Genève, Genève, Switzerland
11:45 AM	CMV Prevention and Treatment: Do It Yourself?... or Current Guidelines Lara Danziger-Isakov, MD, Cincinnati Children's Hospital, Cincinnati, OH, USA
12:00 PM	15-min Panel Discussion

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Primary Audience: PH
Secondary Audience: CTEPH, LF/LTX

Session Summary: This symposium will explore the complex decision making in the care of patients with end stage pulmonary hypertension awaiting lung transplantation. Should patients with pulmonary hypertension ever be offered combined heart and lung transplantation? Should patients with Group 3 pulmonary hypertension be offered vasodilators as they become sicker before transplantation? Can urgency-based allocation systems be fair to patients with pulmonary hypertension?

Chairs: Paul A. Corris, MB, FRCP and Oksana A. Shlobin, MD
 

10:30 AM	CASE PRESENTATION: PAH Patient with Severe RV Dysfunction Prior to Transplant Nicholas Kolaitis, MD, UCSF Medical Center, San Francisco, CA, USA
10:35 AM	DEBATE: ‘All You Need is Lungs’: Lung Transplantation Alone is the Only Type of Organ Transplantation that Should Be Offered in Patients with End Stage PAH Jerome Le Pavec, Sr, MD. Hôpital Marie Lannelongue, Le Plessis Robinson, France
10:50 AM	DEBATE: ‘All You Need is Lungs’: Combined Heart/Lung Transplant Should Be Offered in Patients with End Stage PAH Fernando Torres, MD, UT Southwestern Medical Center, Dallas, TX, USA
11:05 AM	CASE PRESENTATION: Patient with Group 3 Disease and RV Dysfunction Awaiting Transplant Caroline M. Patterson, MD, Papworth Hospital, Cambridge, UK
11:10 AM	DEBATE: Severe PH in Advanced Lung Disease (Group 3) Should Be Treated with Vasodilators (PRO) Steven D. Nathan, MD, Inova Fairfax Hospital, Falls Church, VA, USA
11:25 AM	DEBATE: Severe PH in Advanced Lung Disease (Group 3) Should Be Treated with Vasodilators (CON) Adaani Frost, MD, Baylor College of Medicine, Houston, TX, USA
11:40 AM	CASE PRESENTATION: Patient with PAH Listed for Lung Transplant Who is Getting Sicker Errol L. Bush, MD, Johns Hopkins University, Baltimore, MD, USA
11:45 AM	DEBATE: Let It Be, Let It Be, Speaking of Urgency Allocation, Let It Be: Urgency-Based Allocation Can Be Fair for Patients with PAH (PRO) Thomas M. Egan, MD, MSC. University of North Carolina School of Medicine, Chapel Hill, NC, USA
12:00 PM	DEBATE: Let It Be, Let It Be, Speaking of Urgency Allocation, Let It Be: Urgency-Based Allocation Can Be Fair for Patients with PAH (CON) Helen M. Whitford, MBBS, FRACP, Alfred Hospital, Melbourne, Australia

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Primary Audience: CTEPH
Secondary Audience: PH

Session Summary: The success of Pulmonary Thromboendarterectomy (PTE) has improved over the years due to better understanding of the pathophysiological mechanisms leading to major complications. This knowledge has translated into better ability to prevent them, recognize them early on and manage them more appropriately. This symposium will review specific complications related to PTE and discuss how to manage them to achieve a successful outcome.

Chairs: Elie Fadel, MD and John Cannon, MD
 

2:00 PM	Diagnosed with CTEPH and Decompensated Right Heart Failure: What are the Options? Marc de Perrot, MD, Toronto General Hospital, Toronto, ON, Canada
2:15 PM	ECMO as a Rescue: When, Why and How? David P. Jenkins, FRCS, Papworth Hospital, Cambridge, UK
2:30PM	Major Hemoptysis After PTE: How to Assess It and Treat It? David McGiffin, MD, The Alfred Hospital and Monash University, Melbourne, Australia
2:45 PM	Severe Reperfusion Pulmonary Edema After PTE: Can We Prevent It? Kim M. Kerr, MD, UCSD Medical Center, La Jolla, CA, USA
3:00PM	Residual PH after PTE: When Should I Start to Worry and What Should I Do? Joanna Pepke-Zaba, MD, Papworth Hospital, Cambridge, UK
3:15 PM	Diagnosed with CTEPH and Heparin Induced Thrombocytopenia (HIT): How to Proceed? Olaf Mercier, MD, Centre Chirurgical Marie Lannelongue, Fontenay aux Roses, France
3:30 PM	15-min Panel Discussion

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Primary Audience: HF/HTX
Secondary Audience: MCS

Chairs: Sung-Ho Jung, MD and Marian Urban, MD
 

2:00 PM	(245) LVAD Patients with RV Failure Pre-Heart Transplant Have Reduced Post-Transplant Survival Y. D. Barac, O. Jawitz, J. Schroder, M. Daneshmand, C. Patel, C. Milano. Duke University Medical Center, Durham, NC
2:15 PM	(246) Predictors of Favorable Outcome in Patients Bridged to Transplant with Temporary Mechanical Circulatory Support Devices M. Yin1, O. Wever-Pinzon1, M. R. Mehra2, C. G. Selzman3, A. E. Toll4, W. S. Cherikh4, J. Nativi-Nicolau1, J. C. Fang1, A. G. Kfoury5, E. M. Gilbert1, L. Kemeyou1, S. H. McKellar3, A. Koliopolou3, M. Vaduganathan2, S. Drakos1, J. Stehlik1. 1Cardiovascular Services, University of Utah, Salt Lake City, UT, 2Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA, 3Cardiothoracic Surgery, University of Utah, Salt Lake City, UT, 4United Network for Organ Sharing, Richmond, VA, 5Intermountain Healthcare, Salt Lake City, UT
2:30 PM	(247) In Hospital Outcomes in Adult Congenital Heart Disease Patients with Fontan Undergoing Heart Transplantation - A Decade Nationwide Analysis from 2004 until 2014 G. A. Hernandez1, A. Lemor2, D. Clark3, V. Blumer1, R. Byrne3, R. Fowler3, E. Sandhaus3, A. Weingarten3, B. Frischhertz3, K. Schlendorf3, S. Zalawadiya3, J. Lindenfeld3, J. Menachem3. 1University of Miami, Miami, FL, 2Henry Ford Hospital, Detroit, MI, 3Vanderbilt University, Nashville, TN
2:45 PM	(248) Development and Validation of a Risk Model for Primary Graft Failure after Heart Transplantation and Comparison to the RADIAL Risk Score D. Reichart1, L. Castro2, N. Ruebsamen1, S. Blankenberg1, H. Reichenspurner2, A. Bernhardt2. 1Department of Cardiology, University Heart Center Hamburg, Hamburg, Germany, 2Department of Cardiovascular Surgery, University Heart Center Hamburg, Hamburg, Germany
3:00 PM	(249) Outcomes with Heartsize Matching among Cardiac Transplant Recipients with Pulmonary Hypertension M. Shah1, O. Saeed1, J. Shin1, S. Murthy1, D. B. Sims1, S. Vukelic1, D. Goldstein2, S. J. Forest2, U. P. Jorde1, S. R. Patel1. 1Advanced HF/Transplant Cardiology, Montefiore Medical Center, Bronx, NY, 2Cardiovascular and Thoracic Surgery, Montefiore Medical Center, Bronx, NY
3:15 PM	(250) Insights from High-Performing Heart Transplant Centers across the Recipient Risk-Spectrum T. P. Singh1, M. R. Mehra2, K. Gauvreau3. 1Pediatrics, Harvard Medical School, Boston, MA, 2Medicine, Harvard Medical School, Boston, MA, 3Biostatistics, Harvard School of Public Health, Boston, MA
3:30 PM	(251) A Direct Heart-Transplantation Strategy in Selected Patients on Extra-Corporeal Membrane Oxygenation Achieved Favorable Post-Transplant Outcomes G. Coutance1, G. Lebreton1, N. Jacob1, N. Br´chot2, P. Demondion1, A. Bouglé3, L. Nguyen1, S. Varnous1, A. Combes2, P. Leprince1. 1Cardiac Surgery, Groupe Hospitalier Pitié-Salpêtrière, Paris, France, 2Intensive Care Unit, Groupe Hospitalier Pitié-Salpêtrière, Paris, France, 3Anaesthesiology, Groupe Hospitalier Pitié-Salpêtrière, Paris, France

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Primary Audience: ID
Secondary Audience: HF/HTX, LF/LTX

Session Summary: This joint symposium with the Associação Brasileira de Transplante de Órgãos (ABTO: Brazilian Association of Organ Transplants) will provide the opportunity to exchange experiences between heart and lung transplant centers in Brazil and other centers around the world. Important topics regarding aspects of thoracic organ procurement in different countries and healthy systems as well as the regional variations in disease burden will be discussed.

Chairs: Fernanda Silveira, MD and Paulo M. Pego-Fernandes, MD, PhD
 

2:00 PM	The Largest Public Kidney Transplant Program in the World: What Lessons Should We Learn to Improve Thoracic Organ Transplantation? Jose Osmar Medina Pestana, MD, Hospital do Rim e Hipertensão of Universidade Federal de São Paulo, São Paulo, Brazil
2:15 PM	Few Potential Donors and One of the Largest (Lung) Transplant Systems of the World: How is it Possible? Jonathan Yeung, MD, Toronto General Hospital, Toronto, ON, Canada
2:30 PM	Tuberculosis and Thoracic Organ Transplantation: Pre- and Post-Transplant Management in Endemic Areas Luis Fernando Aranha Camargo, MD, PhD, Universidade Federal de São Paulo/Escola Paulista de Medicina, São Paulo, Brazil
2:45 PM	Tuberculosis and Thoracic Organ Transplantation: Pre- and Post-Transplant Management in Non-Endemic Areas Amparo Sole, MD, Hospital Universitario La Fe, Valencia, Spain
3:00 PM	Heart Transplant and Chagas Disease: Lessons Learned After 30 Years of Experience Tania Mara Varejão Strabelli, MD, Heart Institute São Paulo Medical School, São Paulo, Brazil
3:05 PM	Highlights of Infectious Disease Jonathan M. Hand, MD, Ochsner Medical Center, New Orleans, LA, USA
2:15 PM	Chagas Disease and Heart Failure Management in Non-Endemic Areas Ricardo La Hoz, MD, UT Southwestern Medical Center, Dallas, TX, USA
2:15 PM	15-min Panel Discussion

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Primary Audience: LF/LTX
Secondary Audience: ID

Session Summary: Patients with end stage heart and lung disease outnumber the annual thoracic transplants. Maximizing donor utilization is a key factor to addressing this imbalance, but donor management varies greatly across regions leading to significant heterogeneity in donor utilization. This symposium will describe proven and developing strategies for donor management to increase organ utilization as well as identify future directions and opportunities for improvement.

Chairs: Aleem Siddique, MBBS and Sakhee Kotecha, MBBS (Hons)
 

2:00 PM	Yin and Yang? Goal Directed Thoracic Organ Optimization Does Not Compromise Abdominal Organs Arne Neyrinck, MD, PhD, University Hospitals Leuven, Leuven, Belgium
2:15 PM	Practical Steps to Optimize the Heart and Lungs: The UK Experience Rajamiyer Venkateswaran, FRCS, Wythenshawe Hospital, Manchester, UK
2:30 PM	Carpe Diem - On the Cusp of an Explosion? Research in Donor Management George B. Mallory, Jr., MD, Texas Children’s Hospital, Houston, TX, USA
2:45 PM	Impact of Using Infection Risk Donors Including NAT +HCV Marcelo Cypel, MD, Toronto General Hospital, Toronto, ON, Canada
3:00 PM	Making the Most in DCD Lung Transplant Dirk Van Raemdonck, MD, PhD, University Hospitals, Leuven, Belgium
3:15 PM	Use of Older Donors for Lung Transplantation: How Old is Too Old? Jonathan Singer, MD, MS, UCSF Medical Center, San Francisco, CA, USA
3:30 PM	15-min Panel Discussion

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Primary Audience: MCS
Secondary Audience: PHARM

Chairs: Jan F. Gummert, MD, PhD and Gabriel Sayer, MD
 

2:00 PM	(252) High Afterload Driving Poor Cardiac Output in LVAD Patients is Rectified with Nitrate Therapy A. Rosenbaum, A. Behfar. Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN
2:15 PM	(253) Intravenous Iron Replacement in Patients with Left Ventricular Assist Devices. A Pilot Study A. Mardis1, C. Robinson2, B. Stafford2, J. Patel1, J. Barham2, A. Poole2, S. Branham2, J. Martin2, R. Napier3, P. McCann3. 1Department of Pharmacy, Palmetto Health, Columbia, SC, 2Cardiothoracic Surgery, Palmetto Health, Columbia, SC, 3Cardiology, Palmetto Health, Columbia, SC
2:30 PM	(254) A Trial of Complete Withdrawal of Anticoagulation Therapy in the Heartmate 3 Pump I. Netuka1, P. Ivak1, Z. Tucanova1, S. Gregor1, O. Szarszoi1, J. Rimsans2, J. Connors2, D. Crandall3, P. Sood3, M. Mehra2. 1Institute for Clinical & Experimental Medicine, Prague, Czech Republic, 2Brigham and Women’s Hospital, Boston, MA, 3Abbott, Burlington, MA
2:45 PM	(255) A Long-Term Counterpulsation Heart Assist System Used as a Bridge to Decision in Advanced Congestive Heart Failure T. Symalla1, T. Song1, D. Onsager1, T. Ota1, C. LaBuhn1, P. Combs1, T. Lammy1, S. Patel-Raman2, G. Sayer3, G. Kim3, J. Raikhelkar3, N. Uriel3, V. Jeevanandam1. 1Cardiac Surgery, University of Chicago, Chicago, IL, 2NuPulseCV, University of Chicago, Chicago, IL, 3Cardiology, University of Chicago, Chicago, IL
3:00 PM	(256) Calculation of VAD Cardiac Cycle Volume Using HeartWare Waveform K. L. Kiehl1, B. N. Butzler1, M. T. Saltzberg2, D. Ishizawar2, A. A. Mohammed2, R. L. Kursel2, N. A. Gaglianello2. 1Advanced Heart Failure, Froedtert Hospital, Milwaukee, WI, 2Advanced Heart Failure and Transplant Cardiology, The Medical College of Wisconsin, Milwaukee, WI
3:15 PM	(257) Right Heart Function Worsens in LVAD Patients with Decoupling between Pulmonary Artery and Wedge Pressures> T. Imamura, B. Smith, J. Raikhelkar, D. Rodgers, G. Kim, S. Kalantari, A. Nguyen, N. Narang, B. Chung, I. Ebong, L. Holzhauser, D. Nitta, T. Fujino, C. Juricek, P. Combs, D. Onsager, T. Song, T. Ota, V. Jeevanandam, G. Sayer, N. Uriel. University of Chicago, Chicago, IL
3:30 PM	(258) Outcomes of Obese Patients Bridged to Heart Transplantation with Continuous-Flow Left Ventricular Assist Devices A. K. Okoh1, S. Fugar2, M. Schulthies3, M. Russo1, K. Rivandra1, R. Yanagida1, M. Camacho1. 1RWJ Barnabas Health Newark Beth Israel Medical Center, RWJ Barnabas Health Newark Beth Israel Medical Center, Newark, NJ, 2Division of Cardiology, Rush University Medical Center, Chicago, NJ, 3RWJ Barnabas Health Newark Beth Israel Medical Center, Neward, NJ

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Primary Audience: MCS
Secondary Audience: NHSAH

Session Summary: Patient and healthcare provider partnerships can enhance patient outcomes. Remote care support and monitoring of MCS patients can improve patient independence and positively impact patient care. This joint symposium with the International Consortium of Circulatory Assist Clinicians (ICCAC) will discuss integration of self-care strategies, educational preparation, new technologies maximizing MCS patient management, strategies to reduce morbidity and mortality, the future of MCS support, and challenges and opportunities that advancing technology poses to current practice.

Chairs: Peggy S. Blood, RN, MSN and Simon Maltais, MD, PhD
 

2:00 PM	Under Pressure: Continuous Pulmonary Artery Monitoring and LVAD Finn Gustafsson, MD, PhD, Rigshospitalet, Copenhagen, Denmark
2:15 PM	Q&A
2:20 PM	Care Anywhere: Remote Patient Monitoring Michele C. Kassemos, BSN, UCSF Medical Center, San Francisco, CA, USA
2:25 PM	Q&A
2:40 PM	There's an App for That: Preparing the EMS Thomas Schloeglhofer, MSc, Medical University of Vienna, Vienna, Austria
2:55 PM	Q&A
3:00 PM	Frailty and Exercise Tolerance: How Are They Related? Kavitha Muthiah, MBchB, PhD, St. Vincent's Hospital, Sydney, Australia
3:15 PM	Q&A
3:20 PM	Let the Pacer Do the Work! Conduction Abnormalities in Heart Failure and Their Role in Exercise During VAD Support Van-Khue Ton, MD, PhD, University of Maryland School of Medicine, Baltimore, MD, USA
3:35 PM	Q&A

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Primary Audience: PEDS
Secondary Audience: HF/HTX, MCS

Chairs: Estela Azeka, MD and David L. Sutcliffe, MD
 

2:00 PM	(259) Simultaneous Pediatric Heart-Kidney Transplant Outcomes in the US: A 25 Year National Cohort Study S. Choudhry1, S. W. Denfield1, V. R. Dharnidharka2, Y. Wang1, J. F. Price1, A. G. Cabrera1, H. P. Tunuguntla1, W. J. Dreyer1. 1Texas Children's Hospital, Baylor College of Medicine, Houston, TX, 2Washington University School of Medicine, Saint Louis, MO
2:15 PM	(260) Development and Validation of a Pediatric Heart Failure Risk-Prediction Model for Children Listed for Heart Transplantion in the Current Era C. Chen1, Y. Zhang2, E. Profita1, J. C. Dykes1, E. Liu1, K. Maeda3, C. S. Almond1. 1Pediatric Cardiology, Stanford University, Palo Alto, CA, 2Cardiothoracic Surgery, Clinical and Translational Research Program, Stanford University, Palo Alto, CA, 3Cardiothoracic Surgery, Stanford University, Palo Alto, CA
2:30 PM	(261) Cardiac Transplantation in Fontan Patients Has Equally Excellent Results as Biventricular Congenital Heart Disease Patients K. W. Riggs1, J. T. Broderick1, C. Chin2, R. Bryant III1, F. Zafar1, D. L. Morales1. 1Cardiothoracic Surgery, Cincinnati Children's Hospital, Cincinnati, OH, 2Pediatric Cardiology, Cincinnati Children's Hospital, Cincinnati, OH
2:45 PM	(262) Speaking the Same Language? Assessing Blood Pressure Measurement and Effectiveness in Pediatric VAD Patients C. Villa1, D. Peng2, S. Auerbach3, S. Kindel4, S. Law5, A. Lorts1, M. Mehegan6, M. O'Connor7, M. Ploutz8, D. Rosenthal9, C. VanderPluym10, M. Zinn11, D. Sutcliffe12. 1Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2C.S. Mott Children's Hospital, Ann Arbor, MI, 3Children's Hospital of Colorado, Aurora, CO, 4Children's Hospital of Wisconsin, Milwaukee, WI, 5New York Presbyterian/Morgan Stanley Children's Hospital, New York, NY, 6St. Louis Children's Hospital, Saint Louis, MO, 7Children's Hospital of Philadelphia, Philadelphia, PA, 8Phoenix Children's Hospital, Phoenix, AZ, 9Lucille Packard Children's Hospital, Palo Alto, CA, 10Children's Hospital of Boston, Boston, MA, 11Children's Hospital of Pittsburgh, Pittsburgh, PA, 12Children's Medical Center Dallas, Dallas, TX
3:00 PM	(263) Extracorporeal Membrane Oxygenation Use within 24 Hours of Heart Transplantation in Children: Incidence, Risk Factors, and Outcomes J. Godown1, D. W. Bearl1, C. Thurm2, M. Hall2, B. Feingold3, J. H. Soslow1, B. A. Mettler4, A. H. Smith5, E. Profita6, T. P. Singh7, D. A. Dodd1. 1Pediatric Cardiology, Monroe Carell Jr. Children's Hospital, Nashville, TN, 2Children's Hospital Association, Lenexa, KS, 3Pediatric Cardiology, Children's Hospital of Pittsburgh, Pittsburgh, PA, 4Pediatric Cardiothoracic Surgery, Monroe Carell Jr. Children's Hospital, Nashville, TN, 5Pediatric Critical Care, Monroe Carell Jr. Children's Hospital, Nashville, TN, 6Pediatric Cardiology, Lucile Packard Children's Hospital, Palo Alto, CA, 7Pediatric Cardiology, Boston Children's Hospital, Boston, MA
3:15 PM	(264) Risk Factors for Cardiac Causes of Death in Males with Duchenne Muscular Dystrophy C. A. Wittlieb-Weber1, K. K. Knecht2, C. R. Villa3, C. Cunningham4, M. J. Bock5, K. E. Gambetta6, A. K. Lal7, K. R. Schumacher8, S. P. Law9, S. R. Deshpande10, S. C. West11, J. M. Friedland-Little12, I. D. Lytrivi9, M. A. McCulloch13, R. J. Butts14, D. R. Weber1, J. N. Johnson15. 1University of Rochester Medical Center, Rochester, NY, 2University of Arkansas, Little Rock, AR, 3Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 4Chentel.cunningham@albertahealthservices.ca, Edmonton, AB, Canada, 5Loma Linda University Children's Hospital, Loma Linda, CA, 6Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, 7Primary Children's Hospital, Salt Lake City, UT, 8C.S. Mott Children's Hospital, Ann Arbor, MI, 9Morgan Stanley Children's Hospital of New York Presbyterian, New York, NY, 10Children's National, Washington, DC, DC, 11Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, 12Seattle Children's Hospital, Seattle, WA, 13University of Virginia Children’s Hospital, Charlottesville, VA, 14Children’s Medical Center of Dallas, Dallas, TX, 15Mayo Clinic Children's Center, Rochester, MN
3:30 PM	(265) ABO Incompatible Listing in Early Childhood Results in Earlier Transplantation and Equal Post-Transplant Survival Despite Predominant Use in Sicker Patients S. Urschel1, M. McCoy1, Z. Reinhardt2, A. Dipchand3, R. S. Cantor4, D. A. Koehl4, J. K. Kirklin4, J. A. Ballweg5, K. R. Kanter6, W. Zuckerman7, J. Sparks8, W. F. Carlo9. 1Pediatrics, University of Alberta, Edmonton, AB, Canada, 2Pediatrics, Freeman Hospital, Newcastle upon Tyne, United Kingdom, 3Pediatrics, Hospital for Sick Children, Toronto, ON, Canada, 4Kirklin Institute for Research in Surgical Outcomes (KIRSO), Birmingham, AL, 5Pediatrics, Children's Hospital & Medical Center, Omaha, Omaha, NE, 6Pediatrics, Emory University School of Medicine, Atlanta, GA, 7Pediatrics, Columbia University Medical Center, New York, NY, 8Pediatrics, University of Louisville, Louisville, KY, 9Pediatrics, University of Alabama, Birmingham, AL

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Primary Audience: HF/HTX
Secondary Audience: LF/LTX

Session Summary: The paucity of donors is still the primary limitation for heart transplantation across the world. Too many donor hearts are not accepted for concerns over particular risk factors. This symposium will explore novel ways to expand the donor pool. In a time when the waiting lists grow exponentially, our field must find ways to maximize donor utilization.

Chairs: Kiran K. Khush, MD and James K. Kirklin, MD
 

4:15 PM	Perfect is the Enemy of Good: Using Marginal Donor Hearts David Rabkin, MD, Loma Linda University, Loma Linda, CA, USA
4:30 PM	Riding the Epidemic: Hepatitis C + Donors Should Become Standard of Care Kelly Schlendorf, MD, Vanderbilt University, Nashville, TN, USA
4:45 PM	Distance Makes the Heart Grow Fonder: Miles Should Not Limit Donor Acceptance Christopher Hayward, MD, St Vincent's Hospital, Sydney, Australia
5:00 PM	Love It or Levophed It: High Dose Catecholamine Donor Support and Outcomes After Heart Transplantation Andreas Zuckermann, MD, Medical University of Vienna, Vienna, Austria
5:15 PM	DEBATE: All Nations Should Have an Opt Out System (PRO) Maria Dolores Cosio, MD, Hospital 12 Octubre, Madrid, Spain
5:30 PM	DEBATE: All Nations Should Have an Opt Out System (CON) Peter J. Bergin, MBBS, FRACP, Alfred Hospital, Melbourne, Australia
5:45 PM	15-min Panel Discussion

Visit the ISHLT2019 Online Program Viewer to see the full abstracts from this session

Primary Audience: ID
Secondary Audience: HTX, LTX, PEDS, PHARM

Chairs: Shahid Husain, MD, MS and Erik Verschuuren, MD, PhD
 

4:15 PM	(266) Pentraxin-3 Polymorphisms are Associated with Invasive Pulmonary Aspergillosis after Lung Transplantation A. Van Herck1, A. Sacreas1, T. Heigl1, J. Kaes1, A. Vanstapel1, S. E. Verleden1, D. Lambrechts2, B. M. Vanaudenaerde1, G. M. Verleden1, R. Vos1. 1Lung Transplant Unit, Department of Chronic Diseases, Metabolism & Ageing, University of Leuven, Leuven, Belgium, 2Laboratory of Translational Genetics (VIB Center for Cancer Biology), Department of Human Genetics, University of Leuven, Leuven, Belgium
4:30 PM	(267) Isavuconazonium Pharmacokinetic Interactions with Immunosuppression in Thoracic Transplant Recipients C. Burt1, J. Kozuch1, M. Mariski1, A. Feist1, K. Afshar2, G. Yung2, T. Floreth2, E. Golts3, S. Aslam4. 1Pharmacy, University of California San Diego Health, San Diego, CA, 2Pulmonology, University of California San Diego Health, San Diego, CA, 3Cardiothoracic Surgery, University of California San Diego Health, San Diego, CA, 4Infectious Diseases, University of California San Diego Health, San Diego, CA
4:45 PM	(268) A Comparison of Aspergillus Prophylaxis with Voriconazole versus Isavuconazole in Lung Transplant Recipients D. D. Nanayakkara1, E. Blodget1, S. Ganesh2. 1Infectious Diseases, University of Southern California, Los Angeles, CA, 2Pulmonary and Critical Care Medicine, University of Southern California, Los Angeles, CA
5:00 PM	(269) Quantiferon-CMV Guided Virostatic Prophylaxis after Heart Transplantation G. Poglajen, G. Zemljic, S. Frljak, R. Okrajšek, M. Šebeštjen, A. Cerar, V. Andročec, M. Jaklič, B. Vrtovec. Advanced Heart Failure and Transplantation Center, University Medical Center Ljubljana, Ljubljana, Slovenia
5:15 PM	(270) Does the Use of Serum Ganciclovir Levels to Adjust Valganciclovir Dosing Prevent the Development of CMV Resistance in CMV Mismatched Heart Transplant Recipients? The Mid America Experience J. Linard1, C. Knutson1, R. Wells1, A. M. Borkon2, A. Kao3. 1Cardiac Transplant, Saint Luke's Mid America Heart Institute, Kansas City, MO, 2Cardiothoracic Surgery, Saint Luke's Mid America Heart Institute, Kansas City, MO, 3Cardiology, Saint Luke's Mid America Heart Institute, Kansas City, MO
5:30 PM	(271) Use of Letermovir for CMV Prophylaxis or Treatment in Thoracic Organ Transplant Recipients C. S. King, S. S. Aryal, A. Cochrane, A. Brown, O. Shlobin, K. Ahmad, L. Marinak, M. Fregoso, J. Chun, S. Nathan, P. Shah, S. Desai, S. Katugaha. Inova Fairfax Hospital, Falls Church, VA
5:45 PM	(272) Impact of Prolonging CMV Prophylaxis in High-Risk (CMV D+/R-) Lung Transplant Recipients S. Herrera1, B. Khan2, S. Husain1, M. Binnie2, C. Chow2, T. Martinu2, C. Chaparro2, S. Keshavjee2, L. G. Singer2, J. Tikkanen2. 1Multi Organ Transplant Unit, Division of Infectious Diseases, University Health Network, Toronto, ON, Canada, 2Toronto Lung Transplant Program, University Health Network, Toronto, ON, Canada

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Primary Audience: LF/LTX
Secondary Audience: NHSAH, PHARM

Chairs: Robert D. Levy, MD, FRCPC and Jonathan P. Singer, MD, MS
 

4:15 PM	(273) ISHLT Consensus on Standardization of Bronchoalveolar Lavage in Lung Transplantation T. Martinu1, A. Koutsokera2, C. Benden2, E. Cantu3, D. Chambers4, M. Cypel1, J. Edelman5, A. Emtiazjoo6, A. J. Fisher7, J. R. Greenland8, D. Hayes9, D. M. Hwang10, B. C. Keller11, E. D. Lease12, M. Perch13, M. Sato14, J. L. Todd15, S. Verleden16, J. von der Thüsen17, S. S. Weigt18, S. Keshavjee1, *. On Behalf of ISHLT BAL Stansdardization Workgroup1. 1Toronto Lung Transplant Program, Toronto, ON, Canada, 2University Hospital Zurich, Zurich, Switzerland, 3University Hospital of Pennsylvania, Philadelphia, PA, 4The Prince Charles Hospital, Brisbane, Australia, 5Puget Sound VAMC, Seattle, WA, 6University of Florida, Gainesville, FL, 7Freeman Hospital, Newcastle, United Kingdom, 8University of California San Francisco, San Francisco, CA, 9Nationwide Children’s Hospital, Columbus, OH, 10Toronto General Hospital Research Institute, Toronto, ON, Canada, 11The Ohio State University, Columbus, OH, 12University of Washington, Seattle, WA, 13Rigshospitalet, Copenhagen, Denmark, 14University of Tokyo, Tokyo, Japan, 15Duke University Medical Canter, Durham, NC, 16Katholieke Universiteit Leuven, Leuven, Belgium, 17Erasmus Medical Center, Rotterdam, Netherlands, 18University of California Los Angeles, Los Angeles, CA
4:30 PM	(274) Reduced Frailty after Lung Transplant is Associated with Survival A. Venado1, C. Huang2, D. V. Glidden2, A. Soong1, Y. Gao1, S. Hays1, J. Golden1, J. Kukreja3, L. E. Leard1, R. Shah1, M. Kleinhenz1, J. Greenland1, J. P. Singer1. 1Pulmonary & Critical Care, University of California, San Francisco, San Francisco, CA, 2Epidemiology & Biostatistics, University of California, San Francisco, San Francisco, CA, 3Cardiothoracic Surgery, University of California, San Francisco, San Francisco, CA
4:45 PM	(275) A Combination of Delayed Gastric Emptying and Gastroesophageal Reflux Disease is Associated with Worse Outcomes in Lung Transplantation J. Fernandez-Castillo, E. Huszti, K. C. Zhang, R. Ghany, L. Levy, D. R. Darley, C. Chaparro, J. Tikkanen, S. Keshavjee, L. Singer, J. C. Yeung, T. Martinu. University of Toronto/UHN, Toronto, ON, Canada
5:00 PM	(276) Ten-Year-Experience with Alemtuzumab as Induction Therapy: A Single-Center Analysis of More Than 500 Patients A. Benazzo1, S. Schwarz1, D. Weber2, G. Murakozy1, C. Lambers2, B. Moser1, J. Matilla1, G. Lang2, S. Taghavi1, W. Klepetko1, K. Hoetzenecker1, P. Jaksch1. 1Thoracic Surgery, Medical University of Vienna, Vienna, Austria, 2Division of Thoracic Surgery, Medical University of Vienna, Vienna, Austria
5:15 PM	(277) Extracorporeal Photopheresis Improves Survival Probability and Lowers Hospital-Related Expenses In Lung Transplant Recipients With Bronchiolitis Obliterans Syndrome C. Joukhadar1, R. Knobler2, A. Cho2, U. Just2, G. Muraközy3, P. Jaksch3. 1J&P Medical Research Ltd, Vienna, Austria, 2Department of Dermatology, Medical University of Vienna, Vienna, Austria, 3Division of Thoracic Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria
5:30 PM	(278) Sirolimus + Tacrolimus Maintenance with No Induction Therapy May Maximize Survival in Lung Transplant Recipients M. Wijesinha, J. Hirshon, M. Terrin, L. Magder, C. Brown, K. Stafford, A. Iacono. University of Maryland School of Medicine, Baltimore, MD
5:45 PM	(279) End Stage Renal Disease after Lung Transplantation: An 11-Year National Cohort Study M. Kosztowski, X. Luo, J. Garonzik-Wang, R. Higgins, D. L. Segev, E. Bush. Department of Surgery, Johns Hopkins, Baltimore, MD

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Primary Audience: MCS

Chairs: Ioannis Dimarakis, PhD, FRCS and Amanda R. Vest, MBBS, MPH
 

4:15 PM	(280) Hemodynamic and ECHO Measurements during VA ECMO Weaning Suggest Acceptable LV Unloading A. M. El Banayosy, C. Gordon, M. M. Koerner, M. D. Harper, D. Horstmanshof, D. Vanhooser, J. W. Long, A. El Banayosy. INTEGRIS Baptist Medical Center, Oklahoma City, OK
4:30 PM	(281) Predicting Cardiac Recovery before Durable Left Ventricular Assist Device Implantation in Advanced Heart Failure Patients I. Taleb1, B. D. Horne2, M. Yin1, J. Nativi-Nicolau1, O. Wever-Pinzon1, S. McKellar1, W. T. Caine2, A. Koliopoulou1, R. Alharethi2, A. Kfoury2, E. M. Gilbert1, J. C. Fang1, J. Stehlik1, C. H. Selzman1, S. G. Drakos1. 1University of Utah, Salt Lake City, UT, 2Intermountain Medical Center, Salt Lake City, UT
4:45 PM	(282) Does Indication for LVAD at Time of Implant Matter in Younger Patients? A. Lala1, J. Rowland1, A. Gelijns2, E. Bagiella2, A. Moskowitz2, B. Ferket1, S. Pinney3, M. Miller4, F. Pagani5, D. Mancini6. 1Medicine, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY, 2Population Health Science, Icahn School of Medicine at Mount Sinai, New York, NY, 3Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY, 4NHLBI, Bethesda, MD, 5Cardiothoracic Surgery, University of Michigan, Ann Arbor, NY, 6Medicine, Cardiology, Population Health Science, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, NY
5:00 PM	(283) Cardiac Reverse Remodeling and Recovery in Dilated Cardiomyopathy Medication-Naive Patients Requiring Durable Left Ventricular Assist Device Support I. Taleb1, M. Yin1, A. Koliopoulou1, M. Taleb1, E. Dranow1, L. Kemeyou1, W. T. Caine2, O. Wever-Pinzon1, R. Alharethi2, A. G. Kfoury2, J. Nativi-Nicolau1, J. C. Fang1, J. Stehlik1, C. H. Selzman1, S. G. Drakos1. 1University of Utah, Salt Lake City, UT, 2Intermountain Medical Center, Salt Lake City, UT
5:15 PM	(284) Normalization of Metabolic Status after LVAD Implantation is Associated with Heart Failure Free Survival A. Nguyen, T. Imamura, B. Chung, L. Holzhauser, N. Narang, D. Rodgers, B. Smith, J. Raikhelkar, D. Onsager, T. Song, C. Juricek, T. Ota, V. Jeevanandam, G. Kim, G. Sayer, N. Uriel. University of Chicago, Chicago, IL
5:30 PM	(285) Baseline ECHO a Suitable Screening Tool for LV Recovery during CF LVAD Support S. Rangasamy, O. Saeed, D. B. Sims, J. Shin, S. Murthy, S. Vukelic, D. Goldstein, U. Jorde, S. R. Patel. Cardiology, Montefiore Medical Center, Bronx, NY
5:45 PM	(286) Long-Term Outcome of Patients after Successful LVAD Explant: A EUROMACS Study C. Antonides1, F. Schoenrath2, K. Veen1, R. Muslem1, I. Netuka3, J. Gummert4, B. Meyns5, M. Özbaran6, D. Schibilsky7, T. de By8, K. Caliskan9. 1Department of Cardiothoracic Surgery, Erasmus University Medical Center, Rotterdam, Netherlands, 2Department of Cardiothoracic and Vascular Surgery, German Heart Center Berlin, Berlin, Germany, DZHK (German Center for Cardiovascular Research), partner site, Berlin, Germany, 3Department of Cardiovascular Surgery, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, 4Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center, NRW, Ruhr University Bochum, Bad Oeynhausen, Germany, 5Department of Cardiac Surgery, University Hospitals Leuven, Leuven, Belgium, 6Department of Cardiovascular Surgery, Ege Üniversitesi Tıp Fakültesi, Izmir, Turkey, 7Department of Cardiovascular Surgery, Universitäts-Herzzentrum Freiburg - Bad Krozingen, Freiburg, Germany, 8EACTS, EUROMACS, Windsor, United Kingdom, 9Department of Cardiology, Erasmus University Medical Center, Rotterdam, Netherlands

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Primary Audience: MCS
Secondary Audience: EEP

Chairs: Minoru Ono, MD, PhD and Ivan Knezevic, MD
 

4:15 PM	(287) Predictors and Impact of Vasoplegia after Continuous-Flow Left Ventricular Assist Device Implantation M. Kim, H. Lamba, R. Miller, J. George, S. Sattee, F. Cheema, A. Civitello, R. Delgado, A. Nair, A. Shafii, G. Loor, T. Rosengart, O. Frazier, J. Morgan, S. Chatterjee. Division of Cardiothoracic Transplantation and Mechanical Circulatory Support, Texas Heart Institute at Baylor College of Medicine, Houston, TX
4:30 PM	(288) Longitudinal Trends in Gut Microbial Community Diversity among HF Patients Undergoing LVAD M. Yuzefpolskaya1, B. Bohn D.F.2, D. Onat1, A. Zuver1, D. L. Brunjes1, E. A. Royzman1, A. Pinsino3, K. L. Antler1, J. C. Hupf1, M. B. Dominguez1, A. R. Garan4, H. Takayama5, K. Takeda5, Y. Naka5, P. C. Colombo1, R. T. Demmer6. 1Medicine, Division of Cardiology, Columbia University Medical Center, New York, NY, 2Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, 3Medicine, Jacobi AECOM, Bronx, New York, NY, 4Medicine, Division of Cardiology, Columbia University, New York, NY, 5Surgery, Columbia University Medical Center, New York, NY, 6Epidemiology and Community Health, University of Minnesota, Minneapolis, MN
4:45 PM	(289) Novel Approach to Assess Intraventricular Pressure Difference in Patients with Left Ventricular Assist Device during Ramp Study K. Akiyama1, E. J. Stöhr2, R. Ji3, O. G. Jimenez4, I. Wu5, K. Itatani6, S. Miyazaki7, T. Furusawa7, T. Nishino7, B. J. McDonnell8, A. R. Garan3, M. Yuzefpolskaya3, P. C. Colombo3, Y. Naka1, H. Takayama1, K. Takeda1. 1Cardiothoracic Surgery, Columbia University Medical Center, New York, NY, 2Cardiac Physiology and Health, Cardiff Metropolitan University, Cardiff, United Kingdom, 3Cardiology, Columbia University Medical Center, New York, NY, 4Surgery, Columbia University Medical Center, New York, NY, 5Anesthesiology, Columbia University Medical Center, New York, NY, 6Cardiovascular Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan, 7Cardio Flow Design, Tokyo, Japan, 8Cardiff Metropolitan University, Cardiff, United Kingdom
5:00 PM	(290) Post-Implant Phosphodiesterase-5 Inhibitor Use is Associated with Increased Rates of Late Right Heart Failure after LVAD: An INTERMACS Analysis  E. Grandin1, G. Gulati2, K. Kennedy3, F. Cabezas1, E. Y. Birati4, J. Rame4, P. Atluri5, F. D. Pagani6, J. K. Kirklin7, D. C. Naftel7, R. L. Kormos8, J. Teuteberg9, M. Kiernan2. 1Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, 2Division of Cardiovascular Medicine, Tufts Medical Center, Boston, MA, 3BIDMC Smith Center for Outcomes Research in Cardiology, St. Luke's Mid-America Heart Institute, Kansas City, MO, 4Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, 5Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia, MA, 6Division of Cardiothoracic Surgery, University of Michigan, Ann Arbor, MI, 7Division of Cardiothoracic Surgery, University of Alabama Birmingham, Birmingham, AL, 8Division of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, 9Division of Cardiovascular Medicine, Stanford University Medical Center, Stanford, CA
5:15 PM	(291) Hemodynamic Evaluation of Right Ventricular Function before and after Impella 5.0 Placement for Cardiogenic Shock  A. M. Wolfson, R. M. Cole, D. Emerson, J. Moriguchi, J. S. Chung, D. Ramzy. Cedars-Sinai Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA
5:30 PM	(292) Does Low-Intensity Anticoagulation Using Vitamin K Antagonists Correlate with Factor X Activity Inpatients Implanted with the HeartMate 3 Pump? A Validation Analysis of the MAGENTUM 1 Study J. M. Connors1, I. Netuka2, P. Ivák3, Z. Tučanová3, S. Gregor4, P. Sood5, D. Crandall6, M. R. Mehra7. 1Division of Hematology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 2Institute for Clinical & Experimental Medicine, Prague, Czech Republic, 3Department of Cardiovascular Surgery, Institute for Clinical & Experimental Medicine, Prague, Czech Republic, 4Department of Pharmacy, Institute for Clinical & Experimental Medicine, Prague, Czech Republic, 5Global Clinical Affairs, Heart Failure, Abbott, Burlington, MA, 6Global Clinical, Heart Failure, Abbott, Burlington, MA, 7Brigham and Women’s Hospital, Harvard Medical School, Boston, MA
5:45 PM	(293) Impact of Socioeconomic Status on Outcomes Post-Ventricular Assist Device Implantation J. J. Han1, A. Iyengar1, W. L. Patrick1, J. Goldenring2, M. Molina1, A. Ameer1, M. Helmers1, E. Y. Birati3, P. Atluri1. 1Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, 2Perelman School of Medicine, Philadelphia, PA, 3Cardiology, Hospital of the University of Pennsylvania, Philadelphia, PA

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Primary Audience: NHSAH
Secondary Audience: PEDS, PH, PHARM

Session Summary: This symposium will include novel talks to advance the ways in which we care for organ failure/transplant patients at end of life (EOL). Covered topics will include: emotional support for patients at EOL, collaboration with ethics and palliative care teams, pharmacological management of patients at EOL, palliative care for the pediatric and adult congenital heart disease population, religious/cultural diversity in EOL, and addressing provider burn-out/self-care.

Chairs: Melissa Cousino, PhD, and Rachel M. Crackett, MSc
 

4:15 PM	Beyond Life Support: Emotional Support for Patients at End of Life Bronwyn J. Levvey, RN, Grad Dip Clin Ep, Alfred Hospital, Melbourne, Australia
4:30 PM	It's Complicated: Collaboration and Integration Between Palliative Care, Ethics and Transplant Teams Andrew Courtwright, MD, PhD, University of Pennsylvania, Philadelphia, PA, USA
4:45 PM	Pharmacological Management of the MCS/Transplant Patient at End of Life Steven P. Ivulich, BPharm, Alfred Hospital, Melbourne, Australia
5:00 PM	Bringing PC to PEDS: Palliative Care for Pediatric Transplant and MCS Patients Elizabeth Blume, MD, Children's Hospital, Boston, MA, USA
5:15 PM	Bridging the Gaps: Cultural and Regional Diversity and End of Life Care Rachel Hadler, MD, Hospital of the University of Pennsylvania, Philadelpha, PA, USA
5:30 PM	Self-Care for Us! Provider Heartbreak in Organ Failure/Transplant Care Julie Bidwell, PhD, Emory University, Atlanta, GA, USA
5:45 PM	15-min Panel Discussion

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Primary Audience: PH
Secondary Audience: CTEPH, MCS

Session Summary: In collaboration with the Pulmonary Vascular Research Institute (PVRI), this symposium will provide an overview into the mechanisms, clinical diagnosis and management of chronic right heart failure in left heart disease, scleroderma, and pulmonary hypertension. There will be a focus on the identification of maladaptive remodeling with discussion of the mechanisms contributing to maladaptive remodeling in right heart failure. We will explore the relationship of right ventricular function to functional capacity and highlight a debate on exercise challenge during right heart catheterization.

Chairs: Arun Jose, MD and Marc Simon, MD
 

4:15 PM	Back to the Future 1: Mechanisms of Chronic RV Failure Ryan J. Tedford, MD, Medical University of South Carolina, Charleston, NC, USA
4:30 PM	Back to the Future 2: Metabolic Changes in the Failing Right Heart Evangelos Michelakis, MD, University of Alberta, Alberta, AB, Canada
4:45 PM	Don’t Go Breaking My Heart: Scleroderma Related - a Specific Entity Steven Hsu, MD, Johns Hopkins University, Baltimore, MD, USA
5:00 PM	When the Going Gets Tough, the Tough Get Going: Management of Acute RV Failure John Granton, MD, University of Toronto, Toronto, ON, Canada
5:15 PM	DEBATE: We Should Exercise Our PH Patients During Right Heart Catheterization (PRO) Susanna Mak, MD, PhD, Mount Sinai Hospital, Toronto, ON, Canada
5:30 PM	DEBATE: We Should Exercise Our PH Patients During Right Heart Catheterization (CON) Ivan Robbins, MD, Vanderbilt University, Nashville, TN, USA
5:45 PM	15-min Panel Discussion

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Heart Failure/Transplantation (Adult) (Hibiscus 1 & 2)
(HF/HTX)   Poster Numbers: 944-978, 981-1013

Lung Failure/Transplantation (Adult) (Banda Sea 1)
(LF/LTX)   Poster Numbers: 1014-1063

Mechanical Circulatory Support (Adult) (Timor Sea 1 & 2)
(MCS)   Poster Numbers: 1064-1169

Pediatrics (Banda Sea 2)
(PEDS)   Poster Numbers: 1170-1217

Pulmonary Hypertension and CTEPH (Gardenia 2)
(PH, CTEPH)   Poster Numbers: 1218-1244

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Primary Audience: HF/HTX
Secondary Audience: PHARM

Chairs: Rami Alharethi, MD and Hye Won Lee, PhD
 

6:15 PM	(501) Risk Stratification of Inotropic Therapy for Heart Transplant Candidates in the Era of Ventricular Assist Device Support L. K. Truby1, V. K. Topkara2, S. D. Russell1, C. B. Patel1, R. Agarwal1. 1Duke University Medical Center, Durham, NC, 2Columbia University Medical Center, New York, NY
6:20 PM	(502) Mechanical Circulatory Support Patients Awaiting Heart Transplant with Positive AT1R Antibodies Have Acceptable Outcome Post-Heart Transplant D. H. Chang, J. Patel, M. Kittleson, D. Geft, S. Dimbil, R. Levine, C. Kawata, L. Czer, J. Moriguchi, D. Ramzy, J. A. Kobashigawa. Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
6:25 PM	(503) Predictors and Clinical Outcomes of Vasoplegia in Patients Bridged to Heart Transplantation with Continuous Flow Left Ventricular Assist Devices R. Asleh, H. Alnsasra, S. D. Schettle, R. Taher, S. M. Dunlay, J. M. Stulak, R. C. Daly, A. Behfar, N. L. Pereira, A. L. Clavell, S. Multais, R. P. Frantz, S. S. Kushwaha. Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN
6:30 PM	(504) Elevated Pre-Transplant Neutrophil to Lymphocyte Ratio is Associated with Increased Vasoplegia Syndrome in Cardiac Transplantation N. Ahmed, H. Gandhi, K. Rahgozar, S. Guo, E. Sun, O. Saeed, S. Patel, S. Murthy, J. J. Shin, S. Vukelic, S. Forest, D. J. Goldstein, U. P. Jorde, D. B. Sims. Montefiore Medical Center Albert Einstein College of Medicine, Bronx, NY
6:35 PM	(505) Utility of Routine versus Triggered Evaluations of Rejection Greater Than Two Years Following Heart Transplant J. R. Golbus, M. C. Konerman, K. D. Aaronson. Internal Medicine, University of Michigan, Ann Arbor, MI
6:40 PM	(506) Protocol Endomyocardial Biopsy beyond Six Months - It's Time to Move On K. Oh1, M. H. Mustehsan1, D. B. Sims1, O. Saeed1, S. Vukelic1, J. J. Shin1, S. Murthy1, A. Luke1, S. J. Forest2, D. Goldstein2, U. Jorde1, S. R. Patel1. 1Medicine, Division of Cardiology, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY, 2Cardiovascular and Thoracic Surgery, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY
6:45 PM	(507) Clinical Utility of the IMPACT Score for Mortality Prediction after Heart Transplantation: External Validation Study C. D. Ortiz Bautista1, J. Muniz Garcia2, F. Gonzalez-Vilchez3, J. Segovia Cubero4, M. G. Crespo Leiro5, R. Lopez Vilella6, J. Gonzalez Costelo7, E. Roig Minguel8, J. M. Arizon Del Prado9, J. M. Sobrino Marquez10, I. P. Garrido Bravo11, J. F. Delgado Jimenez12. 1Cardiology, Hospital General Universitario Gregorio Marañón, Madrid, Spain, 2Instituto de Investigaci&ocaute;n Biomédica (INIBIC), Complexo Hospitalario Universitario de A Coruña, A Coruña, Spain, 3Cardiology, Hospital Universitario Marqués de Valdecilla, Santander, Spain, 4Cardiology, Hospital Universitario Puerta de Hierro, Madrid, Spain, 5Cardiology, Complexo Hospitalario Universitario de A Coruña, A Coruña, Spain, 6Cardiology, Hospital Universitario La Fe, Valencia, Spain, 7Cardiology, Hospital Universitario de Bellvitge, Barcelona, Spain, 8Cardiology, Hospital Santa Creu i Sant Pau, Barcelona, Spain, 9Cardiology, Hospital Universitario Reina Sofía, Córdoba, Spain, 10Cardiology, Hospital Universitario Virgen del Rocío, Sevilla, Spain, 11Cardiology, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain, 12Cardiology, Hospital Universitario 12 de Octubre, Madrid, Spain
6:50 PM	(508) One but Not the Same: Risk Factors for Early Post-Transplant Mortality Differ between Medically Managed Patients and Those Bridged to Transplant with Left Ventricular Assist Devices L. K. Truby1, M. Farr2, V. K. Topkara2. 1Duke University Medical Center, Durham, NC, 2Columbia University Medical Center, New York, NY
6:55 PM	(509) Cardiac Transplantation across Preformed HLA-Antibody Barriers: Results of a Peritransplant Desensitization Protocol F. Ius1, S. V. Rojas1, T. Kaufeld1, W. Sommer1, C. Bara1, J. Salman1, T. Siemeni1, R. Poyanmehr1, D. Bobylev1, M. Avsar1, I. Tudorache1, C. S. Falk2, A. Haverich1, G. Warnecke1. 1Department of Cardiothoracic, Transplant and Vascular Surgery, Hannover Medical School, Hannover, Germany, 2Institute of Transplant Immunology, Hannover Medical School, Hannover, Germany
7:00 PM	(510) Treatment of Therapy-Resistant Hyperlipidaemia after Heart Transplant with PCSK9-Inhibitors K. Uyanik-Uenal1, M. Stoegerer-Lanzenberger2, K. Auersperg1, A. Aliabadi-Zuckermann1, G. Laufer1, A. Zuckermann1. 1Department of Cardiac Surgery, Medical University of Vienna (AKH), Vienna, Austria, 23rd Medical Department for Metabolic Disorders and Nephrology, Hospital Hietzing, Vienna, Austria
7:05 PM	(511) Change in Health-Related Quality of Life from Before to Early after Surgery: Findings from the Sustaining Quality of Life of the Aged: Transplant or Mechanical Support (SUSTAIN-IT) Study K. L. Grady1, A. Kao2, M. Dew3, R. Kormos4, A. Andrei1, H. Adam1, Y. Xu1, D. Pham1, L. Pollan1, C. Yancy5, E. Hsich6, W. Cotts7, S. LaRue8, M. Petty9, S. V. Pamboukian10, F. Pagani11, B. Lampert12, M. Johnson13, M. Murray1, K. Tekeda14, M. Yuzefpolskaya15, S. Silvestry16, J. Kirklin17, S. Collum1, J. Spertus2. 1Surgery / Cardiac Surgery, Northwestern University, Chicago, IL, 2Medicine, University of Missouri - Kansas City, Kansas City, MO, 3Psychiatry, University of Pittsburgh, Pittsburgh, PA, 4Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA, 5Medicine, Northwestern University, Chicago, IL, 6Medicine, Cleveland Clinic, Cleveland, OH, 7Medicine, Advocate Christ Medical Center, Oak Lawn, IL, 8Medicine, Washington University, St. Louis, MO, 9Surgery, University of Minnesota Medical Center, Minneapolis, MN, 10Medicine, University of Alabama, Birmingham, AL, 11Surgery, University of Michigan, Ann Arbor, MI, 12Medicine, Ohio State University, Columbus, OH, 13Medicine, University of Wisconsin, Madison, WI, 14Surgery, Columbia University, New York, NY, 15Medicine, Columbia University, New York, NY, 16Surgery, Florida Hospital, Maitland, FL, 17Surgery, University of Alabama - Birmingham, Birmingham, AL
7:10 PM	(512) Intraoperative Perfusion Strategies during Heart Transplantation: Are We Optimizing Renal Protection? N. M. Foley, M. Kuzemchak, Y. Tipograf, C. White-Dzuro, K. Balsara, K. Schlendorf, M. Danter, A. Shah. Cardiac Surgery, Vanderbilt University Medical Center, Nashville, TN

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Primary Audience: HF/HTX
Secondary Audience: NHSAH

Chairs: Alejandro M. F. Bertolotti, Sr., MD and Van N. Selby, MD
 

6:15 PM	(513) Heart Transplantation for Cardiac Amyloidosis - Worthwhile? J. Patel, M. Kittleson, R. Levine, S. Sana, A. Shen, D. Geft, B. Azarbal, E. Kransdorf, J. Kobashigawa. Smidt Heart Institute at Cedars-Sinai, Los Angeles, CA
6:20 PM	(514) Contemporary Outcomes in Patients with Cardiac Amyloidosis Undergoing Heart Transplantation K. Alexander1, C. Barrett2, K. Dobos1, P. Cheng1, R. Liao1, M. Wheeler1, M. Liedtke1, D. Weisshaar3, R. Witteles1. 1Stanford University Medical Center, Stanford, CA, 2University of Colorado, Aurora, CO, 3Kaiser Permanente Santa Clara Medical Center, Santa Clara, CA
6:25 PM	(515) The Evolving Long-Term Outcome of Heart Transplantation in Amyloid Patients J. Patel, M. Kittleson, D. H. Chang, R. Cole, R. Levine, S. Dimbil, A. Jain, B. Kearney, L. Czer, A. Hage, F. Esmailian, J. A. Kobashigawa. Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
6:30 PM	(979) Heart Transplantation in Cardiac Amyloidosis: A Ten Year Experience J. P. Donnelly1, E. G. Soltesz2, M. Z. Tong2, S. A. Hall3, P. Kale3, J. D. Estep1, M. Hanna1. 1Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH, 2Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, Cleveland, OH, 3Annette C. and Harold C. Simmons Transplant Institute, Baylor Scott & White Research Institute, Dallas, TX
6:35 PM	(516) Differential Gene Expression by Race and Impact on Risk after Heart Transplantation Y. Moayedi1, C. S. Fan2, R. J. Miller3, D. Hillier4, M. Tremblay-Gravel1, M. A. Shullo5, R. Woodward4, J. Yee4, C. Manlhiot6, S. Pinney7, S. A. Hall8, K. K. Khush9, H. J. Ross10, J. J. Teuteberg9. 1Medicine, Stanford University, Stanford, CA, 2Biostatistics and Epidemiology, University Health Network , University of Toronto, University of Toronto, ON, Canada, 3Medicine, Division of Cardiology, Stanford University, Palo Alto, CA, 4CareDx, CareDx, Brisbane, CA, 5Pharmacy, West Virginia University, Morgantown, WV, 6Biostatistics, University Health Network , University of Toronto, Toronto, ON, Canada, 7Medicine, Division of Cardiology, Mount Sinai New York, NYC, NY, 8Medicine, Division of Cardiology, Baylor Health Care, Dallas, TX, 9Medicine, Division of Cardiology, Stanford University, Stanford, CA, 10Medicine, Division of Cardiology, University Health Network , University of Toronto, Toronto, ON, Canada
6:40 PM	(517) Comparison of Patients Undergoing Multiorgan Transplantation with or without Prior Ventricular Assist Device M. E. Currie1, D. Banerjee2, Y. Shudo1, B. Lingala1, Y. Zhu1, F. Haddad2, J. Woo1. 1Cardiothoracic Surgery, Stanford University, Stanford, CA, 2Medicine, Stanford University, Stanford, CA
6:45 PM	(518) 10-Year Outcomes in Heart-Kidney Transplant Patients: Is There a Protective Effect for the Donor Heart? L. Czer, M. Kittleson, J. Patel, E. Kransdorf, R. Levine, S. Dimbil, R. Sharoff, B. Kearney, D. H. Chang, M. Hamilton, F. Esmailian, J. A. Kobashigawa. Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
6:50 PM	(520) Improving Nutrition Practices for Critically Ill Postoperative Heart Transplant and Ventricular Assist Device Implant Patients R. Modir1, V. Rao2, J. Teuteberg3, D. Banerjee3, P. Oyer4, Z. Tulu5, E. Hadhazy6, W. Hiesinger4, S. Jimenez3, L. Tu1, C. Hill2. 1Heart Transplant/Clinical Nutrition, Stanford University Hospital, Stanford, CA, 2Anesthesia - Cardiac, Stanford University Hospital, Stanford, CA, 3Cardiovascular Medicine, Stanford University Hospital, Stanford, CA, 4Cardiothoracic Surgery - Adult Cardiac Surgery, Stanford University Hospital, Stanford, CA, 5Solid Organ Transplant, Stanford Health Care, Stanford, CA, 6Stanford Health Care, Stanford, CA
6:55 PM	(521) The BRIGHT Study Shows Geographical Disparities in Body Mass Index among Heart Transplant Recipients M. Alrawashdeh1, M. R. Molina2, S. Beckmann3, K. Denhaerynck3, F. Dobbels4, S. De Geest3. 1Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, 2Hospital of the University of Pennsylvania, Philadelphia, PA, 3Institute of Nursing Science, University of Basel, Basel, Switzerland, 4Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium
7:00 PM	(522) Weight Gain Post Heart Transplantation is Associated with an Increased Risk for Allograft Vasculopathy and Rejection Y. Peled, D. Freimark, E. Nachum, M. Arad, D. Elian, Y. Kassif, N. Shlomo, R. Klempfner, J. Lavee. Sheba Medical Center Tel Hashomer and Tel-Aviv University, Ramat Gan, Israel
7:05 PM	(523) The Gift That Keeps on Giving? The Impact of Donor Coronary Atherosclerosis on the Development of Coronary Allograft Vasculopathy by IVUS Y. Moayedi1, C. S. Fan2, R. J. Miller3, M. Tremblay-Gravel3, M. Kawana3, H. I. Luikart1, N. D'Emilio3, J. Gordon3, J. T. Parizo3, G. Oro3, R. Wainwright3, W. Hiesinger4, C. Manlhiot2, H. J. Ross5, K. K. Khush3, J. J. Teuteberg3. 1Medicine, Stanford University, Stanford, CA, 2Biostatistics, University Health Network, University of Toronto, Toronto, ON, Canada, 3Medicine, Division of Cardiology, Stanford University, Stanford, CA, 4Cardiovascular Surgery, Stanford University, Stanford, CA, 5Medicine, Division of Cardiology, University Health Network, University of Toronto, Toronto, ON, Canada
7:10 PM	(524) Induction with Rabbit-Thymoglobulin (r-ATG) is Associated with Lower Cardiac Allograft Vasculopathy (CAV) S. Madan, S. R. Patel, O. Saeed, S. Forest, W. A. Jakobleff, J. J. Shin, D. B. Sims, D. J. Goldstein, U. P. Jorde. Montefiore Medical Center, Bronx, NY

Primary Audience: ID, BSTR
Secondary Audience: HTX, LTX, MCS, PATH, PEDS

Chairs: Tobias Deuse, MD, PhD and Ignacio Echenique, MD
 

Visit the ISHLT2019 Online Program Viewer to see the full abstracts from this session (Infectious Diseases)
6:15 PM	(525) Cytomegalovirus Infection among Pediatric Heart Transplant Recipients in the Current Era of Valganciclovir Prophylaxis: Impact on Post-Transplant Outcomes B. B. Das1, J. Niu2, P. K. Sue3, B. K. Prusty4. 1Joe DiMaggio Children's Heart Institute, Hollywood, FL, 2Memorial Healthcare System, Hollywood, FL, 3UT Southwestern Medical Center, Dallas, TX, 4University of Wuerzburg, Wuerzburg, Germany
6:20 PM	(526) KPC Klebsiella Identification Significantly Increases Risk of Bronchial Dehiscence in Lung Transplant Recipients J. Suh1, W. Yu1, S. Song1, J. Lee1, M. Park2, S. Kim2, J. Song2, S. Jeong2, H. Paik1. 1Thoracic Surgery, Yonsei University College of Medicine, Seoul, Korea, Republic of, 2Internal Medicine, Yonsei University College of Medicine, Seoul, Korea, Republic of
6:25 PM	(527) Late Onset Invasive Pulmonary Aspergillosis in Lung Transplant Recipients Treated with a Preemptive/ Targeted Antifungal Therapy Strategy: 4 Year Follow Up S. Herrera1, A. Farooq1, S. Davoudi1, T. Martinu2, D. Kumar1, A. Humar1, C. Rotstein1, L. G. Singer2, S. Keshavjee2, S. Husain1. 1Multi Organ Transplant Unit, Division of Infectious Diseases, University Health Network, Toronto, ON, Canada, 2Toronto Lung Transplant Program, University Health Network, Toronto, ON, Canada
6:30 PM	(528) Pre Transplant Interleukin 10 Levels are Higher in Lung Recipients with Post Transplant Infections L. Calahorra1, E. Sarmiento1, J. Cifrian2, C. Bravo3, R. Laporta4, M. Ussetti4, A. De Pablos5, A. Soler6, J. Carbone1. 1Clinical Immunology, Hospital General Universitario Gregorio Marañon, Madrid, Spain, 2Pneumology, Hospital Universitario Marques de Valdecilla, Santander, Spain, 3Pneumology, Hospital Universitario Valle de Hebron, Barcelona, Spain, 4Pneumology, Hospital Universitario Puerta de Hierro, Madrid, Spain, 5Pneumology, Hospital Universitario Doce de Octubre, Madrid, Spain, 6Pneumology, Hospital Universitario La Fe, Valencia, Spain
6:35 PM	(529) Correlation of ImmuKnow Assay Levels with Rejection and Infection after Heart Transplantation D. Nitta, T. Imamura, B. Chung, A. Nguyen, J. Raikhelkar, N. Sarswat, L. Lourenco, B. Smith, L. Holzhauser, G. Kim, I. Ebong, T. Fujino, N. Narang, C. Murks, T. Riley, J. Powers, V. Jeevanandam, G. Sayer, N. Uriel. University of Chicago, Chicago, IL
6:40 PM	(530) IgG2 Insufficiency before Heart Transplantation as a Risk Factor of Early Deadly Infections J. Carbone1, J. Navarro1, I. Sousa2, E. Zatarain2, J. Fernandez-Yañez2, P. Muñoz3, M. Valerio3, E. Sarmiento1. 1Clinical Immunology, Hospital General Universitario Gregorio Marañon, Madrid, Spain, 2Cardiology, Hospital General Universitario Gregorio Marañon, Madrid, Spain, 3Microbiology, Hospital General Universitario Gregorio Marañon, Madrid, Spain,
6:45 PM	(531) Effective Reduction of Postoperative Infections through Routine Preoperative Decolonization with Chlorhexidine and Mupirocin Prior to Left Ventricular Assist Device Implantation S. George1, R. Leasure2, A. McGovern1, H. Setidadi1, D. A. Horstmanshof1. 1INTEGRIS Baptist Medical Center, Oklahoma City, OK, 2College of Nursing, University of Oklahoma, Oklahoma City, OK
6:50 PM	(532) Novel Bacteriophage Therapy for Treatment of Ventricular Assist Device Infections S. Aslam1, V. Pretorius1, E. Adler1, S. Lehman2, S. Morales2, A. Gaidamaka2, C. Furr2, F. Rosas2, K. Bishop-Lilly3, B. Biswas3, B. Sisson4, J. Fackler4, M. Trigg4, R. Schooley1. 1University of California, San Diego, San Diego, CA, 2AmpliPhi Biosciences, San Diego, CA, 3Naval Medical Research Center, Fort Detrick, MD, 4Adaptive Phage Therapeutics, Gaithersburg, MD
6:55 PM	(790) Role of Gallium-SPECT-CT in Predicting Outcomes of Patients with Ventricular Assist Device-Specific Percutaneous Driveline Infection Y. Kimura1, O. Seguchi1, H. Mochizuki1, K. Iwasaki1, K. Toda1, Y. Kumai1, K. Kuroda1, S. Nakajima1, T. Watanabe1, Y. Matsumoto2, S. Fukushima2, M. Yanase1, T. Fujita2, J. Kobayashi2, N. Fukushima1. 1Department of Transplant Medicine, National Cerebral and Cardiovascular Centre, Osaka, Japan, 2Department of Cardiac Surgery, National Cerebral and Cardiovascular Centre, Osaka, Japan
Visit the ISHLT2019 Online Program Viewer to see the full abstracts from this session (Basic Science and Translational Research)
7:00 PM	(534) The Impact of Biomarkers in Predicting the Response to CD34+ Cell Therapy in Non-Ischemic Dilated Cardiomyopathy Patients G. Zemljic, M. Jaklic, A. Cerar, S. Frljak, G. Poglajen, B. Vrtovec. Advanced Heart Failure and Transplantation Centre, University Medical Centre Ljubljana, Ljubljana, Slovenia
7:05 PM	(535) LVAD Therapy Induces Changes in Myocardial Glucose Metabolism and Clock Genes K. Dhar1, A. KC1, F. Qiu2, H. Basma1, J. Um3, D. Anderson1, B. Lowes1. 1Internal Medicine, University of Nebraska Medical Center, Omaha, NE, 2Bio Statistics, University of Nebraska Medical Center, Omaha, NE, 3Surgery, University of Nebraska Medical Center, Omaha, NE
7:10 PM	(536) Sphingosine-1-Phosphate Receptor Agonist Fingolimod Reduces Myocardial Ischemia-Reperfusion Injury and Apoptosis Increasing Long-Term Left Ventricular Function after Heart Transplantation A. Rungatscher, D. Linardi, A. Naseer, R. Mani, S. Hoxha, G. B. Luciani, G. Faggian. Division of Cardiac Surgery, Department of Surgery, University of Verona, Verona, Italy

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Primary Audience: LTX
Secondary Audience: NHSAH, PHARM

Chairs: Jussi Tikkanen, MD, PhD and Ramsey Hachem, MD
 

6:15 PM	(537) Reconsidering Indication of Lung Transplantation for Late-Onset Noninfectious Pulmonary Complications after Hematopoietic Stem Cell Transplantation M. Noguchi, T. F. Chen-Yoshikawa, H. Kayawake, Y. Yamada, Y. Yutaka, D. Nakajima, M. Hamaji, A. Ohsumi, H. Date. Thoracic Surgery, Kyoto University Hospital, Kyoto City, Japan
6:20 PM	(538) Inhaled Cyclosporine-Based Immunosuppression Regimen for Lung Transplant Associated Malignancy I. Timofte1, M. Terrin2, A. Gandhi2, R. Yang2, M. Wijesinha2, R. Vesselinov2, P. McLaughlin2, N. Costa2, D. Kaczorowski2, R. Madathil2, B. Griffith2, A. Iacono2. 1Pulmonary and Critical Care, UMMC, Baltimore, MD, 2UMMC, Baltimore, MD
6:25 PM	(539) CLAD Phenotypes Determined by Change in Spirometric Index Associate with Quantitative Image Analyses S. S. Weigt1, G. Kim1, F. Abtin1, H. Jones2, Y. Shino1, A. DerHovanessian1, D. Sayah1, R. Saggar1, J. P. Lynch III1, J. A. Belperio1, D. J. Ross1, J. Goldin1. 1UCLA, Los Angeles, CA, 2Cedars Sinai, Los Angeles, CA
6:30 PM	(540) Single versus Double Lung Transplantation for Chronic Obstructive Lung Disease(COPD) I. Timofte1, R. Vesselinov2, M. Terrin2, M. Wijesinha2, D. Kaczorowski2, R. Mandathil2, R. Wise3, A. Sternberg3, B. Griffith1, A. Iacono2. 1Pulmonary and Critical Care, UMMC, Baltimore, MD, 2UMMC, Baltimore, MD, 3Pulmonary and Critical Care, Johns Hopkins University School of Medicine, Baltimore, MD
6:35 PM	(541) Risk Factors Associated with Airway Complications after Lung Transplantation A. Bery1, P. Aguilar1, D. Byers1, D. Kreisel2, H. Kulkarni1, R. Nava2, V. Puri2, E. Trulock1, C. Witt1, R. Yusen1, R. Hachem1. 1Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis, MO, 2Division of Cardiothoracic Surgery, Washington University School of Medicine, St. Louis, MO
6:40 PM	(542) Pushing the Envelope in Single Lung Transplantation for Secondary Pulmonary Hypertension: Identifying an Upper Limit of Pressures G. Sunagawa1, M. Kashem1, E. Leotta1, F. Kromah1, S. Brann1, J. Gomez-Abraham1, S. Keshavamurthy1, K. Minakata1, F. Cordova2, Y. Toyoda1, N. Shigemura1. 1Cardiovascular Surgery, Temple University Hospital, Philadelphia, PA, 2Thoracic Medicine and Surgery, Temple University Hospital, Philadelphia, PA
6:45 PM	(543) Predicting Survival for Lung Retransplantation Patients at One and Five Years E. S. Clausen1, J. M. Weber2, M. L. Neely2, S. M. Palmer1. 1Pulmonary and Critical Care Medicine, Duke University, Durham, NC, 2Biostatics and Bioinformatics, Duke University, Durham, NC
6:50 PM	(544) Do the Pretransplant Use of Statins in a Recipient Reduce the Incidence of Primary Graft Dysfunction after Lung Transplant? I. Bello1, E. Coll2, A. Sandiumenge3, L. Romero1, A. Jauregui1, J. Pérez1, J. Ochoa1, S. Peñafiel1, L. Sánchez1, F. Ascanio1, M. Montoya1, E. San Ginés1, J. Sacanell4, C. Berastegui5, C. Vázquez6, I. Los Arcos7, M. Deu1. 1Thoracic Surgery, Vall d'Hebron University Hospital, Barcelona, Spain, 2Organización Nacional de Trasplantes (ONT), Madrid, Spain, 3Transplant Coordination, Vall d'Hebron University Hospital, Barcelona, Spain, 4Intensive Unit Care, Vall d'Hebron University Hospital, Barcelona, Spain, 5Pulmonologist, Vall d'Hebron University Hospital, Barcelona, Spain, 6Anestesiologist, Vall d'Hebron University Hospital, Barcelona, Spain, 7Vall d'Hebron University Hospital, Barcelona, Spain
6:55 PM	(545) Single and Double Lung Transplantation Have Equivalent Functional Status Outcomes at One Year N. K. Ranganath1, T. C. Geraci1, J. Malas1, K. G. Phillips1, D. E. Smith1, B. E. Lonze2, M. B. Lesko3, L. F. Angel3, Z. N. Kon1. 1Cardiothoracic Surgery, NYU Langone Health, New York, NY, 2Surgery, NYU Langone Health, New York, NY, 3Medicine, NYU Langone Health, New York, NY
7:00 PM	(546) Frailty is Associated with Greater Impairments in Health-Related Quality of Life after Lung Transplantation Than Before N. A. Kolaitis1, A. Soong1, Y. Gao1, R. J. Shah1, A. Venado1, S. R. Hays1, J. Kukreja2, J. Golden1, L. E. Leard1, J. R. Greenland1, M. Kleinhenz1, P. P. Katz1, P. D. Blanc1, J. P. Singer1. 1Medicine, University of California, San Francisco, San Francisco, CA, 2Surgery, University of California, San Francisco, San Francisco, CA
7:05 PM	(547) High Lung Allocation Scores Do Not Preclude Improvement in Health-Related Quality of Life after Lung Transplantation A. A. Perez, S. R. Hays, Y. Gao, A. Soong, M. Kleinhenz, L. E. Leard, J. Kukreja, A. Venado, J. A. Golden, R. J. Shah, P. Blanc, J. Greenland, J. P. Singer. UCSF, San Francisco, CA
7:10 PM	(548) Less Delayed Chest Closure, Systemic Edema, and Postoperative Bleeding in Lung Transplantation Using ECMO, Compared with CPB M. Ikeda1, A. Aoyama1, H. Oda1, Y. Yokoyama1, H. Kayawake1, J. Tokuno1, S. Ueda1, F. Gochi1, R. Okabe1, M. Saito1, J. Fukuyama2, M. Okuda2, K. Yamazaki3, K. Minatoya3, Y. Yamada1, Y. Yutaka1, D. Nakajima1, M. Hamaji1, A. Ohsumi1, T. Menju1, T. Sato1, M. Sonobe1, T. F. ChenYoshikawa1, H. Date1. 1Thoracic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 2Medical Equipment, Kyoto University Hospital, Kyoto, Japan, 3Cardiovascular Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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Primary Audience: MCS

Chairs: Snehal Patel, MD and Josef Stehlik, MD, MPH
 

6:15 PM	(561) Unexpected Contribution of Pulsatility to Pump Thrombosis J. Engelman, K. Muthiah, P. Jain, D. Robson, P. Jansz, C. Hayward. Heart Failure and Transplant Unit, St Vincent's Hospital, Sydney, Australia
6:20 PM	(562) CCR5 Expression is Lower in Women, and Mediates Sex-Based Differences in Post-LVAD Right Ventricular Failure A. Nayak1, A. A. Morris1, C. M. Sciortino2, C. Neill3, R. L. Kormos2, C. McTiernan4, J. Larsen3, T. N. Bachman4, K. Hanley-Yanez4, D. M. McNamara2, M. A. Simon2. 1Emory University, Atlanta, GA, 2University of Pittsburgh Medical Center, Pittsburgh, PA, 3University of Pittsburgh School of Medicine, Pittsburgh, PA, 4University of Pittsburgh Vascular Medicine Institute, Pittsburgh, PA
6:25 PM	(563) Impact of Left Ventricular Assist Device Placement on Chronic Kidney Diseases: A Multicenter Longitudinal Study Y. C. Yalcin1, R. Muslem1, K. Veen1, R. J. Tedford2, B. Tomashitis2, Y. Al Najam1, A. Kilic3, B. Houston2, J. J. Brugts1, A. C. Constantinescu1, O. C. Manintveld1, S. Hsu4, A. J. Bogers1, K. Caliskan1. 1Thoraxcenter, Erasmus University, Rotterdam, Netherlands, 2Cardiology, University of South Carolina, Charleston, SC, 3Cardiothoracic Sugery, Johns Hopkins School of Medicine, Baltimore, MD, 4Cardiology, Jonhs Hopkins School of Medicine, Baltimore, MD
6:30 PM	(564) Elevated Shear Associated with MCS Devices Yields Unique Platelet Membrane Lipid Species: Pro-Thrombotic Agonists? A. Sweedo1, L. M. Wise2, Y. Roka-Moiia3, J. Sheriff4, D. Bluestein4, J. G. Purdy2, M. J. Slepian3. 1Biomedical Engineering, University of Arizona, Tucson, AZ, 2Immunobiology, University of Arizona, Tucson, AZ, 3Medicine, University of Arizona, Tucson, AZ, 4Biomedical Engineering, Stony Brook University, Stony Brook, NY
6:35 PM	(565) Time-Dependent Association of Renal Function with Long-Term Survival Following LVAD Implantation H. Vidula, S. McNitt, M. Wang, S. Polonsky, S. Sherazi, I. Gosev, B. Ayers, K. Wood, B. Barrus, J. Alexis, L. Chen, V. Kutyifa, I. Goldenberg. Univ of Rochester, Rochester, NY
6:40 PM	(566) Metabolic Vasoreactivity in the Middle Cerebral Artery of Heart Failure Patients with and without Continuous-Flow Left Ventricular Support R. Ji1, K. Akiyama2, F. Castagna1, A. Pinsino1, J. R. Cockcroft3, M. Yuzefpolskaya1, A. Garan1, V. K. Topkara,1, M. T. Pineda4, H. Takayama4, K. Takeda4, Y. Naka4, P. C. Colombo1, B. McDonnell3, E. J. Stöhr3, J. Z. Willey5. 1Medicine, Columbia University Medical Center, New York, NY, 2Surgery, Columbia University Medical Center, New York, NY, 3Physiology & Health, Cardiff Metropolitan University, Cardiff, CF5 2YB, United Kingdom, 4Cardiothoracic Surgery, Columbia University Medical Center, New York, NY, 5Neurology Stroke, Columbia University Medical Center, New York, NY
6:45 PM	(567) Incidence and Predictors of Long-Term Renal Function Deterioration after Implantation of a Centrifugal, Continuous-Flow Device for Bridge to Transplant N. Kikuchi, A. Yoshimura, H. Hattori, A. Suzuki, T. Shiga, H. Niinami, N. Hagiwara, S. Nunoda. Tokyo Women's Medical University, Tokyo, Japan
6:50 PM	(568) Baseline LVAD Flow is an Important Risk for Hemoresponse to Blood Stream Infection in LVAD Patients with Fixed Cardiac Output N. Bart1, S. Emmanuel2, D. Andresen3, K. Muthiah1, C. S. Hayward1. 1Heart Transplant and Failure, St Vincents Hospital, Sydney, Australia, 2Cardiothoracic Surgery, St Vincents Hospital, Sydney, Australia, 3Infectious Disease, St Vincents Hospital, Sydney, Australia
6:55 PM	(569) What Happens to Right Ventricular Strain and Function Following Tricuspid Valve Repair in Patients Undergoing Implantation of a Left Ventricular Assist Device? O. N. Kislitsina1, A. S. Anderson1, J. D. Thomas1, J. D. Rich1, J. E. Wilcox1, E. E. Vorovich1, A. Zhou2, A. C. Andrei3, R. Harap1, P. M. McCarthy4, C. W. Yancy1, D. T. Pham4. 1Cardiology, Northwestern University Feinberg School of Medicine, Chicago, IL, 2CTU, Northwestern University Feinberg School of Medicine, Chicago, IL, 3Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 4Cardiac Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL
7:00 PM	(570) Cystatin C is Superior to Creatinine for Prediction of Adverse Events in Heart Failure Patients Undergoing LVAD Implant A. Pinsino1, A. Gaudig2, E. A. Royzman2, M. B. Dominguez2, J. Radhakrishnan2, K. Toma2, A. M. Zuver2, M. Tiburcio3, V. Topkara2, A. Masoumi2, A. R. Garan2, H. Takayama3, K. Takeda3, Y. Naka3, R. T. Faillace1, R. T. Demmer4, P. C. Colombo2, M. Yuzefpolskaya2. 1Medicine, Jacobi AECOM, Bronx, NY, 2Department of Medicine, Columbia University Medical Center, New York, NY, 3Department of Surgery, Columbia University Medical Center, New York, NY, 4Epidemiology and Community Health, University of Minnesota, Minneapolis, MN
7:05 PM	(571) Trends and Predictors of Acute Kidney Injury in Patients with and without Chronic Kidney Disease Undergoing Left Ventricular Assist Device Implantation: A Nationwide Inpatient Sample Analysis S. Ranka1, M. Pahuja2, S. Mony3, T. Akhtar1, O. Chahab2, H. Abubakar4, A. Yassen2, T. Ando2, P. Alvarez5, L. Afonso2, A. Brisoulis5. 1John H Stroger Hospital of Cook County, Chicago, IL, 2Detroit Medical Center Wayne State University, Detroit, MI, 3University of South Florida, Tampa, FL, 4Detroit Medical Center Wayne State University, Chicago, IL, 5University of Iowa, Iowa City, IA
7:10 PM	(572) Advanced Kidney Disease in the Left Ventricular Assist Device Population: Impact on Disease Progression, Morbidity and Mortality J. Grinstein, A. Kadakkal, M. Rodrigo, M. Hofmeyer, S. Mohammed, P. E. Craig, R. Torguson, E. Molina, S. Najjar, F. Sheikh. MedStar Heart and Vascular Institute, Washington, DC

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Primary Audience: MCS

Chairs: Cristiano Amarelli, MD and Pavan Atluri, MD
 

6:15 PM	(549) Home Inotropic Therapy Post Left Ventricular Assist Device Placement S. Pauwaa, K. Meehan, L. Kukla, N. Krause, T. Aicher, G. Macaluso, A. Andrade, A. Joshi, C. Sciamanna, M. Dia, P. Pappas, A. Tatooles, W. Cotts. Advocate Christ Medical Center, Oak Lawn, IL
6:20 PM	(550) The Effect of Right Ventricular Arterial Uncoupling on Mortality in Cardiogenic Shock V. Nguyen1, J. McCabe1, C. Mahr1, T. Jones2, M. Tan3, R. Cheng1, T. Dardas1, S. Masri1. 1Department of Medicine, Division of Cardiology, University of Washington, Seattle, WA, 2Department of Medicine, Division of Cardiovascular Medicine, University of Utah, Salt Lake City, UT, 3Department of Medicine, University of Washington, Seattle, WA
6:25 PM	(1119) The Model for End-Stage Liver Disease Score and Survival after the Total Artificial Heart A. Jahangiri1, M. Smallfield1, A. Andreae2, K. Desai2, T. Johnson3, J. Hillaryd3, E. Sawey1, J. Cook4, D. Tang1, V. Kasirajan1, K. B. Shah1. 1Pauley Heart Center, Virginia Commonwealth University, Richmond, VA, 2Virginia Commonwealth University School of Medicine, Richmond, VA, 3Internal Medicine, Virginia Commonwealth University, Richmond, VA, 4Vanderbilt Heart and Vascular Institute, Vanderbilt University Medical Center, Nashville, TN
6:30 PM	(552) Timing of Right Heart Failure after Left Ventricular Assist Device is Associated with Survival after Heart Transplantation E. M. Senser1, F. Cabezas2, E. W. Grandin2. 1Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, 2Cardiology, Beth Israel Deaconess Medical Center, Boston, MA
6:35 PM	(1117) Relationship between Length of Hospital Stay Post LVAD Implant and Survival: The Potential for Understanding a Less Sick Population S. Silvestry1, J. Rogers2, W. Cotts3, M. Slaughter4, S. Prasad5, M. Jacoski6, F. Pagani7, L. Stein8. 1Cardiac Surgery, Florida Hospital Transplant Hospital, Orlando, FL, 2Cardiology, Duke University, Durham, NC, 3Cardiology, Advocate Christ Medical Center, Oak Lawn, IL, 4Cardiac Surgery, University of Louisville, Louisville, KY, 5Cardiac Surgery, University of Rochester, Rochester, NY, 6Medtronic, Framingham, MA, 7Cardiac Surgery, University of Michigan, Ann Arbor, MI, 8Cardiac Surgery, SUNY Downstate, Brooklyn, NY
6:40 PM	(1118) Safety of Mechanical Circulatory Support for Left Ventricular Non-Compaction: Single Center Experience A. Bansal1, F. Akhtar1, M. Bansal2, S. Desai3, D. Jacks1, Y. Gilliland3. 1Cardiothoracic Surgery, Ochsner Clinic Foundation, New Orleans, LA, 2Pathology, Ochsner Clinic Foundation, New Orleans, LA, 3Heart Transplant Med, Ochsner Clinic Foundation, New Orleans, LA
6:45 PM	(895) Tricuspid Regurgitation Predicts Late Onset Right Heart Failure after Left Ventricular Assist Device Implantation O. Gonzalez Fernandez, N. Bouzas Cruz, C. Ferrera Duran, A. Woods, N. Robinson-Smith, S. Tovey, G. Parry, K. Booth, G. MacGowan, S. Schueler. Freeman Hospital, Newcastle upon Tyne, United Kingdom
6:50 PM	(556) Utilization of Combined Mechanical Circulatory Support Devices in Cardiogenic Shock: Insights from the National Inpatient Sample M. Pahuja1, S. Ranka2, S. Mony3, O. Chahab4, T. Ando4, H. Abubakar4, A. Yassen4, P. Alvarez5, L. Afonso6, A. Brisoulis5. 1Detroit Medical Center/Wayne State University, Detroit, ME, 2John H Stroger Hospital of Cook County, Chicago, IL, 3University of South Florida, Tampa, FL, 4Detroit Medical Center Wayne State University, Detroit, MI, 5University of Iowa, Iowa City, IA, 6Detroit Medical Center/Wayne State University, Detroit, MI
6:55 PM	(557) Temporary Mechanical Circulatory Support, a New Paradigm in Bridging Patients to Heart Transplantation: Comparing Outcomes versus Durable Left Ventricular Assist Devices J. S. Chung, D. Emerson, D. Ramzy, A. Akhmerov, R. M. Cole, D. Megna, F. Esmailian, J. Moriguchi, J. A. Kobashigawa, A. Trento. Cedars-Sinai Medical Center, Los Angeles, CA
7:00 PM	(558) Temporary Mechanical Circulatory Support as a Bridge to Heart Transplantation: Insights from the UNOS Database A. K. Okoh1, S. Fugar2, M. Schulthies3, M. Russo1, R. Karanam1, M. Zucker1, R. Yanagida1, M. Camacho1. 1RWJ Barnabas Health Newark Beth Israel Medical Center, RWJ Barnabas Health Newark Beth Israel Medical Center, Newark, NJ, 2Division of Cardiology, Rush University Medical Center, Chicago, IL, 3RWJ Barnabas Health Newark Beth Israel Medical Center, Newark, NJ
7:05 PM	(559) Novel Percutaneous Dual Lumen Cannula Right Ventricular Assist Device Provides Effective Support for Patients after Left Ventricular Assist Device Implantation M. Salna, A. R. Garan, A. Kirtane, D. Karmpaliotis, P. Green, T. Vahl, H. Takayama, J. Sanchez, P. Kurlansky, M. Yuzefpolskaya, P. C. Colombo, Y. Naka, K. Takeda. Columbia University Medical Center, New York, NY
7:10 PM	(560) Direct Cavo-Pulmonary Stent Mounted Right Ventricular Assist Device J. Park, P. Bonde. Yale School of Medicine, New Haven, CT