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Expansion of Donor Pool is INSPIRE-ational

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Anders Andreasson, MD
Freeman Hospital
Newcastle upon Tyne, UK

It took over half a century for the technique to evolve from basic theory to semi-automated circuits fit for clinical use. However, this technology is now rapidly being adopted in transplant centers across the globe. Ex-vivo lung perfusion (EVLP) is one of the hot-topics at this year's ISHLT meeting and with the field in constant evolution the excitement was intense when some of the giants of EVLP took to the stage in the Thursday afternoon Pre-Meeting Symposium 16: Ex-Vivo Lung Perfusion (EVLP): Evolving Strategy for Improved Donor Lung Management.

As the pioneer of clinical EVLP, as well as his recognition for his epic performances that resemble an enthusiastic scientist from a Nordic Noir piece more than a luminary Lund University professor, Prof Stig Steen set the scene with a historical overview of EVLP. Dr. Göran Dellgren and Dr. Bartley Griffith followed up by painting a clear picture of the present-day European and North American experience with the different static EVLP techniques. Dr. Marcelo Cypel furthered this by reviewing the state-of-the-art experimental treatment work carried out on this well suited platform for lung research.

With the recent introduction of portable EVLP, a new era in lung preservation may also be upon us with an opportunity to limit organ ischemic times and potentially improve the outcome of donor lungs already deemed acceptable for transplantation. After Dr. Gregor Warnecke's update on the OCS Lung INSPIRE Trial, this new era doesn't seem far off as long as the current price tag is not of major concern in your transplant unit, some murmured on their way to the coffee break. Dr. Peter Hopkins also addressed this in a very sensible way in the closing presentation on cost justification and criteria definitions in this blooming field.

Disclosure Statement: the author has no conflicts of interest to report.

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