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This month, JHLT features incisive editorials on 2 issues of cardinal clinical importance. Sharon Hunt, the 2012 ISHLT Lifetime Achievement Awardee, provides a poignant reflection on the notion of age thresholds for cardiac transplantation (link to article). Drs. Abdallah G. Kfoury and Jon Kobashigawa react to the recently implemented high priority allocation system in Canada for the sensitized candidate (link to article).

  • ♦  Outcomes of cardiac transplantation in septuagenarians (Goldstein)
    Link to Article

Selected septuagenarians with advanced heart failure can derive great benefit from cardiac transplantation, although survival is inferior to that of an immediately younger sexagenarian cohort. Most of the mortality risk is seen in the first year after transplantation.

  • ♦  Voriconazole is associated with cutaneous squamous cell carcinoma in lung transplant recipients (Singer)
    Link to Article

These authors suggest that caution should be taken when using voriconazole in lung transplantation because this drug increases the already high risk for squamous cell cancer in this population.

  • ♦  Effects of exercise training on exercise capacity and quality of life in patients with a left ventricular assist device: A preliminary randomized controlled trial (Hayes)
    Link to Article

In a randomized comparison, the authors find that exercise training is feasible and safe in patients with a durable left ventricular assist device. Trends toward greater improvement in exercise capacity and quality of life after exercise training point to need for further investigation in a larger trial.

  • ♦  Long-term treatment, tolerability, and survival with sub-cutaneous treprostinil for severe pulmonary hypertension (Sadushi-Koliçi)
    Link to Article

First-line treatment of severe pre-capillary pulmonary hypertension with sub-cutaneous treprostinil is safe and efficacious over many years. If up-titration beyond 6 months is tolerated, effective doses are reached and outcomes are good.

  • ♦  Highly sensitized patients in cardiac transplantation: Early outcomes from the Canadian Prioritized Organ Sharing Program (Chih)
    Link to Article

This preliminary review demonstrates satisfactory short-term outcomes from the new Canadian 4S-prioritized national organ sharing program. Long waiting times and significant mortality persists for sensitized patients. Without the current system, however, many may not have received a transplant, as suggested by the two-thirds of transplanted patients who received a non-local donor organ.


mandeep mehraI am very pleased to report that the JHLT now boasts a 1 year Impact Factor of 4.332 (last year 3.426) and a 5 year Impact Factor of 3.521 (last year 3.096).

The 2011 journal citation reports were released on June 28th 2012 and now rank the JHLT:

♦ 1st among all Solid Organ Specific transplant Journals
♦ 3rd among all Transplantation Journals
♦ 6th among all Respiratory Disease Journals
♦ 8th among all Surgical Specialty Journals
♦ 22nd among all Cardiovascular and Circulatory Disease journals

These rankings reflect a significant increase from last year. As an example, the JHLT was ranked 7th in the Transplantation category and 34th in the Cardiovascular and Circulatory disease category in the 2010 Citation Report.

The Impact Factor is one way of adjudicating journal ranking and prestige - While imperfect in its methodology and subject to year by year shifts, this metric does allow for a comparison across a "level" playing field in comparison with other journals in various disease and category specific areas. On all counts of modern metrics such as the Eigen Factor, the H-Index, the Article Influence Score and Immediacy Index, the JHLT has demonstrated superlative gains this year.

These rankings are a credit to the confidence placed by the ISHLT fraternity of colleagues in the editorial team, the hardworking group of diligent editorial consultants, reviewers and authors who chose to publish in our journal. This performance amplifies our relentless focus on scientific rigor, quality as well as intended journal diversity beyond transplantation into areas such as Mechanical Circulatory Support and Pulmonary Hypertension have yielded these outcomes.

Sincerely yours,


Mandeep R. Mehra, MD
JHLT Editor-in-Chief