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links imageFEATURED LINKS LECTURE:

How Can You Mend A Broken Heart?

MYOCARDIAL RECOVERY OF THE FAILING HUMAN HEART:
IS IT POSSIBLE?


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STAVROS G DRAKOS, MD, PhD
ISHLT Links Associate Editor (Cardiology)
Assistant Professor of Medicine
Medical Director, Cardiac Mechanical Support Program
University of Utah School of Medicine
Salt Lake City, Utah, USA

stavros.drakos@u2m2.utah.edu


The enormous medical burden of heart failure, along with the scientific challenge to defy biologic limits, spurs an intense interest in regenerating and restoring the function of a failing heart. However, the classic view is that in response to severe injury, the human heart has limited ability to recover.

In this presentation we will briefly describe the variety of clinical settings and syndromes that reverse cardiac remodeling by focusing on mechanical unloading-induced cardiac recovery through the clinical application of ventricular assist devices.

One goal from the field of clinical and translational research is to identify biomarkers and clinical characteristics that will predict which broken-hearted individuals might achieve myocardial recovery. By examining the accumulated information from these patients we will be better poised to understand and manipulate cardiac recovery both in experimental and clinical settings.

SLIDE PRESENTATION (PDF)



Disclosure Statement: The author has no conflicts of interest to disclose.